Published in Medical Letter on the CDC and FDA, September 11th, 2005
"Sabin strains of poliovirus used in the manufacture of oral poliovirus vaccine (OPV) are prone to genetic variations that occur during growth in cell cultures and the organisms of vaccine recipients. Such derivative viruses often have increased neurovirulence and transmissibility, and in some cases they can re-establish chains of transmission in human populations," scientists in the United States and Russia report.
"Monitoring for vaccine-derived polioviruses is an...
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