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HIV/AIDS Genomics and Genetics

Diversity of thymidine resistance genotypes HIV discussed

Published in Medical Letter on the CDC and FDA, September 18th, 2005

A researcher discusses the diversity of thymidine analogue resistance genotypes among newly diagnosed HIV-1-infected people in a recent issue of the Journal of Antimicrobial Chemotherapy.

According to recent research from the United States, "The introduction of highly active antiretroviral therapy (HAART) has resulted in a significant decrease in HIV and AIDS-related mortality and morbidity. However, these treatments can select for drug-resistant viruses, which are associated with poor virological responses to the antiretroviral therapy and possible loss of clinical benefit. Drug-resistant viruses can also be transmitted between individuals."

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