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HIV/AIDS-Associated Infection

Cotrimoxazole prophylaxis reduces morbidity/mortality among HIV- family members

Published in Medical Letter on the CDC and FDA, September 25th, 2005

Cotrimoxazole prophylaxis by HIV-infected persons reduces morbidity and mortality among HIV-uninfected family members.

According to a recently published report from Uganda, "The effect of cotrimoxazole prophylaxis taken by persons with HIV on community health and antimicrobial resistance is unknown." The "effect of cotrimoxazole prophylaxis taken by persons with HIV on morbidity, mortality, and antimicrobial resistance of diarrheal pathogens infecting their HIV-negative family members" was assessed in a prospective cohort in rural Uganda.

"A total of 879 persons with HIV and 2771 HIV-negative family members received weekly home-visits. After 5...

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