Neosporosis Vaccine Development
Microneme antigen NcMIC1 protects against cerebral neosporosis
Published in Medical Letter on the CDC and FDA, September 25th, 2005
According to a study from Switzerland, "NcMIC1 is a 460 amino acid Neospora caninum microneme protein implicated in host cell adhesion and invasion processes. In this study, we assessed the potential protectivity of NcMIC1-based vaccination against experimental N. caninum infection in mice, employing both recombinant antigen vaccines and DNA vaccines. Recombinant NcMIC1 (recNcMIC1) was expressed in Escherichia coli as gluthatione-S-transferase-fusion protein."
"The corresponding NcMIC1 cDNA was cloned into the...
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