Medical Letter on the CDC and FDA

Generic Drugs - FDA approves NDA for cholestyramine for oral suspension

Generic Drugs - Pharma company announces tentative approval for Ondansetron Hydrochloride Tablet

Generic Drugs - Tentative FDA approval granted to market Glimepiride Tablets

HIV/AIDS - Leishmaniasis in HIV-infected patients investigated

HIV/AIDS Diagnosis - CD4 count among normal north Indians lower than in Western populations

HIV/AIDS Pathogenesis - Resting naive CD4+ T cells massively infected and eliminated

HIV/AIDS Risk Assessment - Written/electronic STD testing protocols promotes risk assessment questioning

HIV/AIDS Risk Factors - Polygamy and extramarital sex are risk factors for HIV transmission in Nigeria

HIV/AIDS Therapy - Nandrolone decanoate benefits HIV-infected men with weight loss

HIV/AIDS Vaccine Develoment - Determinants of HIV resistance to gp41-derived peptides examined

HIV/AIDS Vaccine Development - Different epidemic potentials of HIV-1B and C subtypes reported

HIV/AIDS Vaccine Development - Global enterprise uses scientific/financial resources to develop AIDS vaccine

HIV/AIDS Vaccine Development - Measles vaccine vector primes antibodies against HIV-1 epitopes

HIV/AIDS Vaccine Development - Soluble HIV-1 envelope glycoprotein trimers characterized

HIV/AIDS Vaccines - Findings advance knowledge in HIV/AIDS vaccines research

HIV/AIDS-Tuberculosis Coinfection - Elevated CCR5/CXCR4/cytokines persistently increase viral load in TB coinfection

Health Policy - Public policy change on firearms and youth in California reported

Healthcare Policy - Reproductive health group comments on Susan Wood's resignation from OWH post

Hookworm Vaccine Development - Antibodies against hookworm larvae protein reduce hookworm infection

Hypertension - FDA grants expanded label for Ventavis

IGF-1 Deficiency - FDA approves Increlex for short stature from severe primary IGF-1 deficiency

Imaging - Real-time MRI-guided stenting achieved in porcine model

Infectious Disease - New drugs may soon be available for some previously ignored worst diseases

Influenza - CDC's recommended influenza prioritization schedule includes FluMist

Influenza - GlaxoSmithKline announces U.S. FDA approval of FLUARIX

Influenza Vaccine - Company announces favorable results of FDA inspection of Fluvirin facility

Information Technology - One-hundredth eCTD submission completed by tech firm for pharma clients

Information Technology - Taratec audit performed for U.S. FDA regulatory compliance

Insulin Resistance - FDA approves qualified health claim for chromium picolinate and diabetes risk

Interarterial Block - Interpreters of ECGs should seek interatrial block in all 12 leads

Legal Issues - U.S. solicitor general recommends LabCorp's petition in patent case be denied

Legionellosis - Proactive approach can prevent nosocomial Legionnaires' disease

Lipid Therapy - Intervention program increased prescription rate of lipid modifying therapy

Lymphocytosis - Diagnostic criteria for monoclonal B-cell lymphocytosis outlined

Malaria Therapy - Future clinical research on malaria discussed

Malaria Vaccine - Reference standard for antibody to Plasmodium protein characterized

Measles Vaccine Development - Measles vaccine vector induces broadly neutralizing antibodies against HIV-1

Mechlorethamine - Analysis of nitrogen mustard in topical drugs reported

Medical Devices - First European spinal surgeries follow CE marking, ISO certification of devices

Medical Devices - U.S. FDA grants clearance to sell female incontinence sling in U.S. market

Medical Devices - U.S. NIH grant awarded to fund study of stroke recovery system

Mycobacterium Tuberculosis - Host control of MTB regulated by 5-lipoxygenase-dependent lipoxin production

Mycobacterium Tuberculosis - Inducible promoter generates a conditional auxotroph of M. tuberculosis

Mycobacterium Tuberculosis - MTB PknH gene deletion confers higher bacillary load during chronic infection

Mycobacterium Tuberculosis Diagnostics - Genotyping rapidly detects rifampin/isoniazid resistance in MTB complex isolates

Neonatal Sepsis - Neonatal sepsis associated with bacterial contamination of intravenous fluids

Nosocomial Infections - ESBL-producing K. pneumoniae outbreak related to onychomycosis discovered

Nosocomial Infections - Toxicogenomic effects of peracetic acid on P. aeruginosa characterized

Obstetrics - New findings in the area of obstetrics described

Pain Management - FDA grants orphan drug designation to CGX-1160 for chronic intractable pain

Parvovirus - Virulent variants of parvovirus minute virus investigated

Pertussis Vaccines - New research in the area of pertussis vaccines detailed

Philanthropy - Pharma company donates 3 million treatments of antiviral Tamiflu to WHO

Pneumococcal Vaccines - Research in pneumococcal vaccines provides new insights

Polio Vaccine Develoment - MRC-5 cells provide alternative for oral polio vaccine production

Pseudomonas Aeruginosa Outbreaks - Nosocomial outbreak caused by multidrug-resistant IMP-producing bacteria

Recalls - U.S. FDA announces recall of Medline brand of alcohol-free mouthwash

SARS - Assays assess neutralizing antibody activity against SARS-associated coronavirus

SARS - Recent findings in SARS described

SARS Vaccine Develoment - Expression of SARS nucleocapsid protein in E. coli achieved

SARS Vaccines - Researchers detail new studies and findings in the area of SARS vaccines

Sexual & Reproductive Health - FDA defers decision on Plan B over-the-counter application

Sexually Transmitted Diseases - Increasing rates of STDs in homosexual men in Europe and U.S. examined

Shigella Sonnei Outbreaks -  Shigella sonnei outbreak in Canary Islands produced by a single strain

Smallpox Vaccine Development - No oropharyngeal vaccinia virus detected after smallpox vaccination

Smallpox Vaccine Development - Vaccinia strain used for smallpox vaccine 1937 to 1970 characterized

Smallpox Vaccine Development - Vaccinia virus L5r gene encodes protein required for cell entry

Staphylococcus Vaccine Development - Vaccine protects against Staphylococcus aureus infection

Stem Cell Research - State of California grants manufacturing license for cell processing facility

Thalidomide - Dermatological indications and side effects of thalidomide reported

Tobacco Use - Looking to the future: Helping 33 million smokers quit

Tuberculosis - Predictors of recurrent pulmonary tuberculosis identified

Tuberculosis Pathogenesis -  M. tuberculosis plcD gene may be involved in tuberculosis pathogenesis

Tuberculosis Reinfection - Rate of reinfection TB after successful treatment higher than rate of new TB

Tuberculosis Vaccine - TB vaccines in developing countries need to block immunopathological responses

Vaccine Development - Recombinant proteins produced by vaccinia virus in perfusion bioreactor