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Medical Letter on the CDC & FDA

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Cytomegalovirus Retinitis Prognosis



Detectable plasma CMV load at CMV retinitis diagnosis associated with mortality



October 23rd, 2005

A detectable plasma cytomegalovirus load at the time of CMV retinitis diagnosis is associated with mortality.

According to a recently published report from the United States, "The amount of cytomegalovirus (CMV) DNA in the blood (CMV load) may be a marker for detection of resistant CMV."

"A total of 165 patients with AIDS and CMV retinitis had CMV load measurements (plasma and leukocyte) and cultures performed every 3 months; these measurements were correlated with CMV resistance to antiviral drugs and CMV retinitis progression (from masked readings of retinal photographs).

"Detectable plasma and leukocyte CMV loads were...


Source: Medical Letter on the CDC & FDA (2005-10-23)

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