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Medical Letter on the CDC & FDA

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HIV/AIDS Diagnosis



Rapid HIV antibody assays for detecting recent seroconversion modified



October 23rd, 2005

Scientists have modified rapid human immunodeficiency virus (HIV) antibody assay protocols for detecting recent HIV seroconversion.

According to recent research from the United States, "Assay protocols of three rapid human immunodeficiency virus (HIV) assays, OraQuick-1/2, SeroStrip-1/2, and Determine-1/2, were modified to detect recent HIV seroconversion using a higher dilution of serum specimens. Optimal predilution of specimens resulted in negative test results during early periods of seroconversion (about 6 months), when antibody levels were low."

"A total of 269 seropositive specimens from routine HIV type 1 testing and from commercial sources...


Source: Medical Letter on the CDC & FDA (2005-10-23)

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