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Medical Letter on the CDC & FDA

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Diagnostics



GC-MS detects prenatal exposure to environmental toxicants and their metabolites



October 23rd, 2005

Gas chromatography-mass spectrometry is used to detect prenatal exposure to environmental toxicants and their metabolites.

According to a study from the United States, "We developed a sensitive method to detect several classes of pesticides and their metabolites in maternal and cord whole blood using electron-impact gas chromatography-mass spectrometry (GC-MS).

"The method can detect parent and metabolite compounds at levels of <0.10 and 0.20 mcg/mL, respectively, with high accuracy and recovery."

"Analysis of blood from mother-infant dyads from an area of high pesticide use in the Philippines showed detectable levels of...


Source: Medical Letter on the CDC & FDA (2005-10-23)

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