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Medical Letter on the CDC & FDA

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Drug Safety



Liposomal amphotericin B safe/effective for pediatric visceral leishmaniasis



October 23rd, 2005

Liposomal amphotericin B is safe and effective for the treatment of pediatric visceral leishmaniasis.

In a recent report, researchers in France described "liposomal amphotericin B (AmBisome) use as first line treatment of pediatric visceral leishmaniasis" and evaluated "the incidence of the disease in southern France" from a retrospective "chart review of children referred for visceral leishmaniasis from 1996 to 2003."

"Thirty-two children under 15 years of age and suffering from visceral leishmaniasis were treated with liposomal amphotericin B as first line treatment. Clinical and biological features were usual: age <5 years, no immunodeficiency,...


Source: Medical Letter on the CDC & FDA (2005-10-23)

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