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Medical Letter on the CDC & FDA

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Environmental Health



HPLC-MS/MS method to measure environmental phenols in urine developed



October 23rd, 2005

Researchers have developed an automated on-line column-switching HPLC-MS/MS method with peak focusing for the determination of nine environmental phenols in urine.

According to a study from the United States, "We developed a method using isotope dilution on-line solid-phase extraction (SPE) coupled to high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) for the determination in urine of nine environmental phenolic compounds: Bisphenol A; 4-tert-octylphenol; o-phenylphenol; 2,4-dichlorophenol; 2,5-dichlorophenol; 2,4,5-trichlorophenol; 2,4,6-trichlorophenol; benzophenone-3 (2-hydroxy-4-metoxybenzophenone); and triclosan...


Source: Medical Letter on the CDC & FDA (2005-10-23)

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