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Food Allergies
Proteolytic processing of the peanut allergen Ara h 3
October 23rd, 2005
Scientists describe proteolytic processing of the peanut allergen Ara h 3 in a recent issue of Molecular Nutrition and Food Research. According to a study from the Netherlands, "The allergen Ara h 3 has been purified recently from peanuts. In contrast to recombinant Ara h 3, a 60-kDa single-chain polypeptide, the allergen isolated from its native source is extensively proteolytically processed. The characteristic proteolytic processing for 11S plant storage proteins of the glycinin family is observed for Ara h 3 yielding an acidic and a basic subunit, bound by a disulfide bridge. In addition to this, proteolytic truncation is observed for the acidic subunit but...
Source: Medical Letter on the CDC & FDA (2005-10-23)
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