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West Nile Virus
Immunoassay to detect anti-West Nile virus IgM antibodies developed
October 23rd, 2005
Scientists have developed a duplex microsphere-based immunoassay for detection of anti-West Nile virus and anti-St. Louis encephalitis virus IgM antibodies. "West Nile (WN) virus was introduced into the United States in 1999, when the first human cases of WN fever and encephalitis appeared in New York City. From there, the virus has spread throughout North America, in some areas co-circulating with the related flavivirus St. Louis encephalitis (SLE) virus. Public health laboratories currently use an immunoglobulin M (IgM) antibody capture enzyme-linked immunosorbent assay (MAC-ELISA) as a primary test for human serodiagnosis, followed by a confirmatory plaque-reduction...
Source: Medical Letter on the CDC & FDA (2005-10-23)
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