HIV/AIDS Diagnostics
Genotypic assay detects all HIV-1 protease and reverse transcriptase subtypes
Published in Medical Letter on the CDC and FDA, October 23rd, 2005
"Genotypic assays are used often to guide clinicians in decisions concerning the treatment of patients. An optimized sequence-based genotypic assay was used to determine the whole protease and reverse transcriptase (RT) gene, including the gag cleavage site region and RNase H region," scientists in Belgium report.
"Since non-B subtypes are increasing in countries where subtype B was the most prevalent subtype, and treatment becomes more available in developing countries where the epidemic is characterized by a high prevalence of non-B subtypes, it was...
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