Published in Medical Letter on the CDC and FDA, October 30th, 2005
Study 1: Researchers have investigated the induction of IgG to Plasmodium falciparum variant surface antigens during the transmission season.
"The acquisition of immunoglobulin (Ig) G to variant surface antigens (VSAs) seems important for the development of protective immunity against malaria. Unlike VSAs expressed by parasite isolates associated with uncomplicated malaria, VSAs expressed by parasite isolates associated with severe malaria (VSA(SM)) are frequently recognized by IgG," investigators in Denmark and Sudan report.
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