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Genetics & Genomics

Beta-lactamase gene identified from an enterohemorrhagic E. coli O157:H7 outbreak strain

Published in Medical Letter on the CDC and FDA, November 13th, 2005

A beta-lactamase gene was identified from an enterohemorrhagic Escherichia coli O157:H7 outbreak strain.

"A family outbreak of enterohemorrhagic Escherichia coli (EHEC) 0157: H7 infection occurred in October 2003 in the Hiroshima prefecture, Japan. Four isolates of EHEC O157: H7, 03064, 03065, 03066 and 03067, were recovered from a 1-year-old daughter, mother, father and 3-year-old daughter, respectively," researchers in Japan report.

"All EHEC 0157: H7 isolates were positive for Stx1 and Stx2 Shiga toxins. Surprisingly, DNA fingerprinting profiles obtained by PFGE showed that the first isolate, 03064, had unique Xbal and Blnl profiles...

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