Medical Letter on the CDC and FDA

HIV/AIDS Vaccine Development - CD8⁺ lymphocytes do not protect against acute SIV superinfection

HIV/AIDS Vaccine Development - HIV trials feasible with fewer animals if subjects repeatedly challenged with low doses

HIV/AIDS-Related Infection - Incidence of esophageal candidiasis in AIDS patients in Europe is declining

HIV/AIDS-Related Infection - Nocardiosis to be considered in HIV patients with low CD4 counts

HIV/AIDS-Related Infection - Oral lesions are indicators of infection in HIV/AIDS

Healthcare Access - Peters-Belson method advised for study of health care disparities from complex survey data

Helicobacter Pylori - Probiotic supplementation improves tolerance to H. pylori eradication therapy

Hematology - Method developed to automate glycerolization of red blood cells

Hepatitis B Vaccine - Alaska Natives immunized at birth are protected against hepatitis B

Hepatitis B Virus - Vaccination reduces hepatitis B prevalence in U.S. children

Herpes Simplex Virus Type 2 Risk Factors - Fatal herpes simplex virus type 2 infection occurred in Darier disease

Hookworm Vaccine Development - Hookworm heme-binding glutathione transferase has vaccine potential

Imaging - U.S. FDA clearance of high-frequency intravascular imaging catheter announced

Infectious Diseases - Disease susceptibility to tuberculosis is dependent on host genetic predisposition

Influenza - Antivirals and vaccines maker offers pandemic flu plans

Influenza Vaccines - Dutch company updates progress in scale-up of cell-culture-based influenza vaccine programs

Information Technology - ECG monitoring services provider achieves Mortara Certified Partner status

Ischemia - Therapy potential of mitochondrial biogenesis regulatory program in ischemia discussed

Kidney Disease - U.S. NIH study shows kidney failure rates stabilized, racial disparities persist

Legal Issues - U.S. marshals seize infusion pumps made by Baxter after warnings ignored

Leukemia - U.S. Food and Drug Administration grants fast track designation for Troxatyl

Malaria - HRP2 antigen levels remain elevated for at least 7 days after malaria treatment

Malaria Drugs - HIV-1 protease inhibitors have antimalarial activity

Malaria Therapy - Nitric oxide bioavailability restoration may be an effective antimalaria therapy

Malaria Therapy - Trimethoprim-sulfamethoxazole is efficacious for uncomplicated malaria

Malaria Vaccine - Binding hot spot for invasion inhibitory molecules on P. falciparum antigen identified

Malaria Vaccine - Polymorphisms in malaria T cell epitopes not selected by immune pressure

Malaria Vaccine - Protective human immunity is a vaccine discovery tool for falciparum malaria

Malaria Vaccine Development - Changes in host cell tropism limits efficacy of malaria vaccine

Medicaid - U.S. HHS approves Medicaid reform demonstration in Florida

Medical Devices - Company files application with U.S. FDA for polymer coated surgical mesh product

Medical Devices - SELDI-TOF mass spectrometry proposed for biomarker discovery and serum proteomic study

Medical Devices - U.S. FDA grants 510(k) clearance for urine preservative transport

Melanoma - Ultraviolet A exposure increases melanoma-endothelial adhesion in mouse model

Meningitis Risk Factors - Meningococcal disease rate higher in microbiologists than general U.S. population

Meningitis Vaccine Development - Anti-idiotypic antibody is candidate for meningitis vaccine

Meningitis Vaccine Development - Meningococci from invasive meningococcal disease cases in Canada characterized

Mosquito-Borne Disease - Reports describe recent advances in mosquito-borne disease research

Mosquito-Borne Disease - Wash resistance predicts longevity of long-lasting insecticidal nets

Mumps Vaccine - Plaque reduction neutralization is sensitive, specific for wild-type mumps virus

Non-Small Cell Lung Cancer - Enrollment opens in Phase III study of treatment for non-small cell lung cancer

Norovirus Outbreaks - Majority of Norovirus outbreaks transmitted by human contact

Nosocomial Infections - Global nosocomial safety campaign with guidelines on hand hygiene launched

Nosocomial Infections - Two nosocomial Mycoplasma pneumoniae epidemics in Korea separated by 3 years

Obesity Genomics and Genetics - Mature adipocytes play active role in obesity-related inflammation

Packaging - U.S. FDA approves Flexbumin, an albumin solution, in a flexible container

Patents - U.S. patent awarded for UCOE gene expression technology

Pediatric Vaccine - Electronic registries may allow children to receive late routine vaccinations

Personnel - Genomics research organization names MaryAnn Guerra chief operating officer

Pertussis Vaccines - New research in the area of pertussis vaccines detailed

Pharmaceutical Research - RiVax maker provides business and clinical update; RiVax phase I trial complete

Physical Activity - Exercise can decrease health care utilization and costs in Medicare retirees

Professional Education - Knowledge solutions company rolls out Medicare Part D nine-course curriculum

Proteomics - Protein measurement company receives $500,000 SBIR grant from U.S. National Science Foundation

Radiology - Regulatory exemptions for humans in radiology research outlined

Respiratory Medicine - Genetically related RSV circulate the same years within neighboring countries

Respiratory Medicine - Long-term outcome good for simple aspergilloma and satisfactory for complex aspergilloma

Respiratory Medicine - Pneumonia and pulmonary TB most common respiratory tract infections in hospitalized travelers

SARS - Reports advance knowledge in SARS research

Scabies - HTLV-1 infection is an important co-factor related to Norwegian scabies in Peru

Sepsis Therapy - Drotrecogin alfa not beneficial for severe sepsis with low risk of death

Smallpox Vaccines - Reports describe recent advances in smallpox vaccines research

Sociology Research - Many health workers in Nigeria discriminate against patients with HIV/AIDS

Stem Cell Research - Government contractor, AntiCancer Inc. collaborate to develop neural diseases therapy

Streptococcal Vaccine Development - Prospects for group A streptococcal vaccine reviewed

Surgical Techniques - Trends in ablative techniques for Barrett esophagus are investigated

Trypanosoma Cruzi - DHEA enhances reduces level of Trypanosoma cruzi parasites

Tuberculosis - Recurrent tuberculosis in HIV-infected children is common in a high-burden TB setting

Tuberculosis Risk Factors - Risk of tuberculosis infection in children related to number and duration of exposure

Urology - U.S. FDA grants marketing clearance for urological neurostimulation device

Vaccine Safety - Data mining methods on the Vaccine Adverse Event Reporting System database compared

Vaccinia Virus - PCR is most sensitive for vaccinia virus detection in patient specimens

X-Ray Exposure - Germ cell-transmitted alteration may be initiated by preconceptual maternal X-ray exposure