Drug Delivery
Intramuscular administration of antimalarial drug arteether appears to be most potent
Published in Medical Letter on the CDC and FDA, November 27th, 2005
According to recent research from India, "The pharmacokinetics of alpha- and beta-diastereomers of arteether, a potent erythrocytic schizontocidal agent, and their active metabolite dihydroartemisinin were studied in male Sprague-Dawley rats after oral, intramuscular and intravenous administrations."
S. Sabarinath and colleagues at the Central Drug Research Institute described, "Oral and intramuscular studies were carried out at three dose levels at 9, 17.5, and 30 mg kg-1. The ratio of alpha- and...
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