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Isoniazid is cost-effective for reducing TB burden in recently converted persons

Published in Medical Letter on the CDC and FDA, November 27th, 2005

Isoniazid is cost-effective for reducing tuberculosis burden in recently converted persons.

According to recent research from Germany, "The aim of the present study was to perform a cost-effectiveness analysis in young and middle-aged adults with latent tuberculosis (TB) infection in Germany. A Markov model simulated the progression of 20- and 40-year-old close contacts of active TB cases over 20 years.

"Health and economic outcomes of isoniazid (INH) chemoprevention versus no intervention were compared. The analysis determined the incremental cost-effectiveness ratio in terms of cost per quality-adjusted life year and the difference between numbers...

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