Genetics & Genomics
Iodine doses change multiple oxidative stress-related gene expression in rat model
Published in Medical Letter on the CDC and FDA, December 4th, 2005
"Organic iodides have been shown to induce thyroid hypertrophy and increase alterations in colloid in rats, although the mechanism involved in this toxicity is unclear. To evaluate the effect that free iodide has on thyroid toxicity, we exposed rats for 2 weeks by daily gavage to sodium iodide (NaI)," researchers in the United States report.
C.M. Glatt and colleagues working with the U.S. Environmental Protection Agency proposed, "To compare the effects of compounds with alternative mechanisms (increased thyroid hormone metabolism and decreased thyroid hormone...
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