Medical Letter on the CDC and FDA

Antibiotic Resistance - Antimicrobial resistance is common in Shiga toxin-producing E. coli

Breast Cancer Therapy - Desferal inhibits breast tumors and does not interfere with doxorubicin

Pneumococcal Disease - Prevalence of pediatric pneumococcal serotypes is increased in elderly

Staphylococcus Aureus - Community-associated methicillin-resistant Staphylococcus aureus is on the rise

Tuberculosis Diagnosis - C-18-carboxypropylbetaine improves sensitivity of sputum smear microscopy

Acute Myeloid Leukemia - Clofarabine's duration of response improves outcome for elderly AML patients

Acute Peripheral Arterial Occlusion - European Medicines Agency grants orphan drug designation for alfimeprase

Alzheimer Disease - Further proposals filed with U.S. FDA for NTP test kit premarket approval

Amyotrophic Lateral Sclerosis - Pharma company gets U.S. NIH grant for ALS drug research

Anthrax - Sortase genes srtA and srtB are important for Bacillus anthracis growth in macrophages

Anti-Infectives - U.S. FDA recognizes alcohol-based hand sanitizers as safe and effective for consumer use

Antimicrobials - Xanthohumol is a broad-spectrum anti-infective agent

Auricular Chondritis - Ear piercing associated with auricular chondritis outbreak

Avian Influenza - U.S. FDA opens door for further testing of investigational veterinary formula

Awards - U.S. Army awards grant to support development of wound dressing for burns

Awards - U.S. government awards safety syringe contract for global HIV/AIDS initiative

Behavioral Medicine - POZ parties are an emerging risk for HIV-infected men who have unprotected sex with men

Breast Cancer - Estrogens play important role in early pathologic process towards breast cancer

Business & Finance - Oncology-focused pharmaceutical company reports third quarter $8.9M net loss

Business Update - Company updates financial status, anticipates anthrax vaccine delivery in 2006

Cancer Epidemiology - Increased BMI is associated with higher risk of pancreatic cancer in men

Cancer Research - Investigational new drug application granted for modified version of RigScan CR

Cancer Therapy - U.S. FDA approves of intravenous administration of Oncaspar

Chlamydia - National performance measure improves chlamydia screening

Clinical Trials - Collaboration to evaluate idebenone compound SNT-MC17 in Friedreich's ataxia

Clinical Trials - Danish Medicines Agency grants approval for phase I trial of stroke treatment

Clinical Trials - Data show levalbuterol inhalation treatment effective for COPD patients

Clinical Trials - Phase II study to evaluate satraplatin in patients with metastatic breast cancer

Clinical Trials - Trial of GI monitoring capsule complete, U.S.FDA 510(k) submission pending

Collaborations - Akorn signs deal with India-based firm to develop and supply an oral anti-infective drug product

Collaborations - Commercial alliance signed for tramadol products

Colon Cancer - E-cadherin regulates the association between beta-catenin and actinin-4

Complementary & Alternative Medicine - Personalized medicine company launches consultancy and training service

Depression - U.S. FDA approves new drug application for citalopram hydrobromide tablets

Diabetes Therapy - Some foods, beverages could hold clues for future diabetes treatment

Diagnostics - Real-time PCR targets a unique chromosomal sequence of Yersinia pestis

Diagnostics - Researchers provide details of new studies and findings in the area of diagnostics

Diet & Nutrition - Nutrient density score helps develop healthy diet

Drug Delivery - U.S. Army awards grant to investigate transdermal delivery of dengue vaccine

Drug Development - Amoxicillin Pulsys phase III trial set to begin following meeting with U.S. FDA

Drug Development - Clinical data show faster symptom relief with Patanase compared with Nasonex for allergic rhinitis

Drug Development - Mandatory U.S. FDA review of all pharmaceutical direct-to-consumer advertising is proposed

Drug Development - Technology development organization creates Taiwan R&D Center

Drug Development - TertaQ and pharmaceutical company form strategic plan to accelerate Australian drug development

Endometrial Cancer - Endometrial cancer risk is increased with estrogen plus progestin therapy

Environmental Health - Army program reduces children's pesticide exposure

Environmental Health - Reports published on the growing health effects of global warming

Finance - Ophthalmics-focused drug maker posts net loss of $0.35 per share