Medical Letter on the CDC and FDA

Lyme Disease - Report compares multiplex assays for detecting Borrelia in Ixodes nymphs

Medical Devices - U.S. FDA uses judgment in applying standards for medical devices

Tick-Borne Disease - Robotic method for high-throughput molecular testing of ticks has been developed

Anti-Infectives - U.S. FDA clears the ON-Q SilverSoaker antimicrobial catheter

Antibiotic Resistance - Report reviews evolution of antibiotic resistance in S. pneumoniae in Brittany

Apoptosis - Retinol induces cytochrome c release from rat liver mitochondria

Asthma Therapy - Montelukast is beneficial in treating asthma in preschool children

Attention Deficit Hyperactivity Disorder - Psychopharmacologic drugs advisory committee supports safety and efficacy of Daytrana

Avian Influenza - U.S. FDA issues investigational new animal drug number for study of avian flu on pigs

Bacillus Anthracis - Anthrax toxin enhances VCAM-1 expression in endothelial cells

Behavioral Medicine - Adolescent alcohol use disorders predict adult borderline personality

Bioterrorism - Expert panel evaluates implementation of Project BioShield and procurement of biodefense vaccines

Cancer Therapy - Analysis of phase III kidney cancer trial to be completed in March 2006

Cardiology - Fish oil may prevent potentially deadly decline in heart rate variability

Cerivastatin - Mitochondria are involved in exercise-induced cerivastatin muscle toxicity

Cervical Cancer - Pharma company submits biologics license application for papillomavirus vaccine to U.S. FDA

Clinical Trials - Racial minorities are willing to participate in health research when there is an opportunity

Community Acquired Pneumonia - U.S. FDA provides guidance on a pivotal phase III clinical protocol evaluating Cethromycin in CAP

Complementary & Alternative Medicine - Study shows Ierobina is an antidyspeptic agent

Consumer Alert - Consumers warned about bacterially contaminated Miracle II Neutralizer and Gel

Crohn Disease - U.S. FDA grants clearance to begin phase II clinical trial of Crohn disease treatment

Diabetes - U.S. FDA activates diabetes drug investigation

Diabetes Pathogenesis - Deficiency in Ikk beta gene enhances arsenic-induced gadd45 alpha expression

Diabetes Pathogenesis - Lower catecholamine-induced lipolysis and HSL expression are linked to obesity

Diet & Nutrition - High carotenoid-rich vegetables and fruit intake reduced plasma C-reactive protein in men

Drug Delivery - Rutin and quercetin gastro-resistant microparticles have been obtained by spray-drying

Drug Delivery - U.S. FDA approves Hylenex

Drug Development - Biologics license application filed with U.S. FDA for Hunter syndrome treatment

Drug Development - Favorable regulatory developments reported for Veronate may help smallest neonates

Drug Development - Phase I/II trial to evaluate bone formation in spine with tissue repair cell product

Drug Development - Positive meeting with U.S. FDA reported for development of lung cancer drug

Drug Development - Positive results reported from first of two phase III trials of ophthalmic anti-infective solution

Drug Development - Protein engineering company establishes proof of concept with TNF-alpha antagonist

Drug Development - Regulatory status of U.S. Navy's proposed RESUS trauma trial updated

Drug Development - Tentative U.S. FDA approval issued for sertraline hydrochloride tablets

Drug Development - U.S. FDA grants approval for Kogenate FS with Bio-Set for patients with hemophilia A

Electrocardiography - U.S. FDA Electrocardiogram Warehouse provides clinical utility

Electronic Medical Records - Community Health Network of West Virginia selects Medsphere OpenVista

Endocrinology - E.U. marketing authorization application for primary IGFD treatment submitted

Environmental Health - Exposure to farming environments as a child does not increase type 1 diabetes risk

Food-Borne Illness - Biomarkers of marine neurotoxicant domoic acid have been identified

Food-Borne Illness - Method is developed to measure putrescine and cadaverine in seafood

Gastric Cancer - U.S. FDA grants priority review to Taxotere for advanced gastric cancer

Gastric Cancer Risk Factors - Report describes cell proliferation and inflammation before and after H. pylori eradication

Gynecological Cancer Risk Factors - Report asserts no proof of carcinogenic properties for combined therapy

HIV/AIDS Epidemiology - AIDS triples the mortality of adults aged 25-44 years in Pointe-Noire

HIV/AIDS HAART - Replication-competent HIV persists in patients with uninterrupted HAART