Medical Letter on the CDC and FDA

Diet & Nutrition - Urinary phyto-estrogen concentrations in U.S. population are presented

Respiratory Diseases - U.S. CDC issues new guidelines for detection of tuberculosis

Sexually Transmitted Disease - Trends in sexual behavior in general and minority populations are diverging

Vaccine Safety - Poliovirus vaccine shedding is minimal among people infected with HIV

Abortion - Studies evaluate misoprostol use to terminate pregnancies in Latin America

Addiction Medicine - Agency issues approvable letter for Vivitrol for treatment of alcohol dependence

Adolescent Health - Psychotropic drug prescriptions for U.S. teens surge 250% over 7-year period

Adverse Drug Reaction - QT prolongation and torsades de pointes occur in methadone users

Allergy & Immunology - Article reviews desloratadine for treating allergic inflammatory disorders

Attention Deficit Hyperactivity Disorder - U.S. FDA issues approvable letter for Daytrana methylphenidate transdermal system

Avian Influenza - Ingestible avian influenza formulation eradicates virus strain in independent lab tests

Bioterrorism - Biodefense support agreement inked with GE Healthcare

Birth Defects - U.S. statistics for incidence of 18 major birth defects are released

Botulism Vaccine - Anti-neurotoxin antibody production is enhanced by subcomponents of C. botulinum hemagglutinin

Buruli Ulcer - Researchers detail new studies and findings in the area of Buruli Ulcer

Business Update - Medical technology company reports marketing progress of microendoscope for breast cancer

Cancer Research - U.S. DOD awards $1.5 million in research funding to Nebraska cancer center

Cancer Therapy - Supplemental BLA submitted for Avastin in relapsed metastatic colorectal cancer

Chronic Lymphocytic Leukemia - NDA filed for Genasense Injection

Clinical Trials - Cancer cell-inhibiting drug shows significant activity in elderly leukemia patients

Clinical Trials - Drugmaker files responses to FDA's approvable letters on NDAs for oxymorphone ER and IR tablets

Clinical Trials - Researcher presents argument for using new method in clinical trials

Clinical Trials - U.S. phase 3 trial of mannitol in people with suspected asthma begins patient enrollment

Collaborations - Company developing blood substitute engages Regulus for U.S. FDA services

Constipation Therapy - Report reviews the role of serotonergic agents for primary chronic constipation

Coronary Artery Disease - U.S. FDA clears NT-proBNP test for new risk stratification use

DNA Research - Human papillomaviruses may be spread through blood

Dengue Virus - Dengue virus type 4 has a higher rate of geographic dispersal than Dengue virus type 2

Diagnostics - Infectious Cryptosporidium oocysts detected by cell culture immunofluorescence assay

Diagnostics - PillCam SB designated as first-line diagnostic tool under revised Tennessee Medicare policy

Diagnostics - U.S. FDA clearance granted for new claim with avian influenza A and B test

Diagnostics - U.S. FDA grants market clearance for ischemia modified albumin test run on Roche analyzers

Diagnostics - VNTR and FliP are rapid and discriminatory Mycobacterium tuberculosis typing methods

Disease Control - Antigenic divergence of B. pertussis circulating isolates has evolved over time

Drug Development - Approval granted from U.S. FDA for Zonisamide capsules, 25 mg, 50 mg & 100 mg

Drug Development - Biopharma company pursues parallel efforts in U.S. and Europe for its NE-180 program

Drug Development - Depakote ER approved for acute manic or mixed episodes associated with bipolar disorder

Drug Development - INDA filed with U.S. FDA for monoclonal antibody treatment of Hodgkin lymphoma

Drug Development - Investigational new drug application submitted to U.S. FDA for Delta opioid agonist compound

Drug Development - NDA filed with U.S. FDA for mesalamine treatment of ulcerative colitis

Drug Development - Review focused on regulatory issues for plant-made pharmaceuticals and vaccines

Drug Development - U.S. FDA grants approval for zonisamide capsules for epilepsy

Drug Development - U.S. FDA grants fast track designation for esterase inhibitor for hereditary angioedema

Drug Development - U.S. FDA grants orphan drug designation for CellCept in myasthenia gravis

Drug Development - U.S. FDA issues approval for orally disintegrating drug for depression

Drug Safety - Agency to strengthen research and communication with AHRQ

Euvolemic Hyponatremia - U.S. FDA approves VAPRISOL for the treatment of euvolemic hyponatremia

Food Safety - U.S. FDA issues recall of tropical fruit ackee because of possible health risks

Gastroenterology - Review focused on clinical trial site organization and management

Gastroesophageal Reflux Disease - Esophageal pH monitoring is focus of review

Generic Drugs - Pharma company announces final U.S. FDA approval for generic seizure medication

Generic Drugs - Pharma company receives approval to market generic Dostinex

Generic Drugs - U.S. FDA grants approval for generic muscle relaxant baclofen tablet

Genetic Diversity - African-American populations have greater genetic diversity compared to Caucasians

Genetics & Genomics - South African GB virus C genotypes inhibit HIV replication

Geriatrics - Chief medical officer of SCAN Health Plan participates in White House Conference on Aging

HIV/AIDS Pathogenesis - Primer removal not a necessary component of HIV-1 reverse transcription