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Tuberculosis Therapy

Point mutations in M. tuberculosis genes linked to drug resistance are identified

Published in Medical Letter on the CDC and FDA, February 5th, 2006

Scientists have identified point mutations in Mycobacterium tuberculosis genes associated with drug resistance.

According to recent research published in the Journal of Microbiological Methods, "Global public health is threatened by the emergence of potentially dangerous antibiotic drug-resistant strains of Mycobacterium tuberculosis. Point mutations in certain M. tuberculosis genes are associated with the resistance of M. tuberculosis strains to antibiotic drugs. The purpose of this study was to develop a suitable microarray-based protocol for the detection of point mutations in M. tuberculosis genes associated with drug...

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