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U.S. patent granted covering use of drug Xanafide for treating multiple types of cancers

Published in Medical Letter on the CDC and FDA, February 26th, 2006

Xanthus Life Sciences, Inc. announced it has been issued U.S. Patent No. 6,989,390 covering the use of Xanthus' cancer drug, Xanafide, a new salt form of amonafide (a topoisomerase 2 inhibitor) for the treatment of a broad range of cancers, including breast, colon, lung, prostate and leukemia.

Xanthus recently initiated a multicenter phase 2 study in patients with secondary acute myeloid leukemia (AML) based on data from a phase 1 study, which showed encouraging activity and an acceptable safety profile. Secondary AML refers to those patients who have developed AML based on an antecedent condition, either myelodysplastic syndrome or prior regimens of chemotherapy or...

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