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Ricin Vaccines

Positive phase I results of RiVax vaccine announced

Published in Medical Letter on the CDC and FDA, March 5th, 2006

DOR BioPharma, Inc., (DOR) announced results of a phase I clinical trial of RiVax, a recombinant vaccine against ricin toxin, that has been completed by investigators at the University of Texas Southwestern Medical Center (UT Southwestern) led by Dr. Ellen Vitetta, director of the Cancer Immunobiology Center at UT Southwestern.

The results of the phase I safety and immunogenicity dose-escalation study indicate the vaccine is well-tolerated and induces antibodies in humans that neutralize ricin toxin. The outcome of the study was to be published in the online edition of the Proceedings of the [U.S.] National Academy of Sciences.

The pilot,...

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