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Enrollment opened in phase 2 trial of DNA vaccine against cytomegalovirus

Published in Medical Letter on the CDC and FDA, March 5th, 2006

Vical Incorporated (VICL) announced that enrollment has opened in its phase 2 trial of a DNA vaccine against cytomegalovirus (CMV). The phase 2 trial will be conducted at U.S. transplant centers in donors and patients undergoing stem cell transplants

Success in this patient population would support Vical's expansion of studies of its CMV vaccine into other transplant settings and the general population.

CMV is a herpes virus that infects more than half of all adults in the United States by age 40, and is even more widespread in developing countries. While a healthy immune system typically protects an infected person against CMV disease, it rarely...

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