Carcinogenesis
Acrylamide and its metabolite glycidamide are genotoxic in mice
Published in Medical Letter on the CDC and FDA, April 26th, 2006
"The recent discovery of acrylamide (AA), a probable human carcinogen, in a variety of fried and baked starchy foods has drawn attention to its genotoxicity and carcinogenicity. Evidence suggests that glycidamide (GA), the epoxide metabolite of AA, is responsible for the genotoxic effects of AA. To investigate the in vivo genotoxicity of AA, groups of male and female Big Blue (BB) mice were administered 0, 100, or 500 mg/L of AA or equimolar doses of GA, in drinking water, for three to four weeks," scientists in the United States report.
"Micronucleated reticulocytes (MN-RETs) were...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Medical Letter on the CDC and FDA
More Articles from Medical Letter on the CDC and FDA
- Polymerase Chain Reaction
PCR method to detect toxin genes in enterotoxigenic Escherichia coli has been developed - Salmonellosis
Drug-resistant Salmonella outbreak is linked to ground beef in U.S. - Salmonellosis
Sample preparation affects recovery of Salmonella from fruit - Acne
Reliant Technologies announces U.S. FDA clearance of the Fraxel Laser for acne and surgical scars - Adverse Drug Reaction
Fosphenytoin may cause hemodynamically unstable bradydysrhythmias - Allergy Medicine
Method to determine phenylephrine, chlorpheniramine, and methscopolamine is developed - More from this issue of Medical Letter on the CDC and FDA
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
