Published in Medical Letter on the CDC and FDA, April 26th, 2006
According to the review from the United States, "The prototypical xanthine oxidase (XO) inhibitor allopurinol, has been the cornerstone of the clinical management of gout and conditions associated with hyperuricemia for several decades. More recent data indicate that XO also plays an important role in various forms of ischemic and other types of tissue and vascular injuries, inflammatory diseases, and chronic heart failure."
"Allopurinol and its active metabolite oxypurinol...
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