Susan Hasty, Publisher
Table of Contents . . . May 10th, 2006
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Medical Letter on the CDC and FDA | Other Publications
Depression Therapy - Suicidality is slightly increased in children taking antidepressant drugs
Drug Resistance - T cell cytokine responses are dependent on multidrug resistance protein-1
Nosocomial Infection - Clostridium infection is increasing in elderly patients discharged from hospitals
Outbreaks - Norovirus causes about one-quarter of gastroenteritis outbreaks in U.S.
Stroke - Folic acid fortification reduces stroke mortality in Canada and U.S.
Anthrax - Recent studies from the United States add new data to anthrax research
Attention Deficit Hyperactivity Disorder - U.S. FDA approves methylphenidate patch to treat ADHD in children
Avian Influenza - Measures to eradicate highly pathogenic avian influenza in Europe are examined
Avian Influenza - Pennsylvania Governor Rendell says Pennsylvania is ready in the event of avian influenza
Awards - IncisionTech wins Medical Design Excellence Award for work on device for Patton Surgical
Bacteriology - Gene products required for polysialic acid synthesis in Escherichia coli K1 are reported
Baculovirus - Method to estimate baculovirus titer based on viable cell size has been developed
Blood Transfusion - Immucor announces Capture-S (Syphilis) and CMV assays have been cleared for use on the Galileo
Botulinum Toxin Vaccine - DOR BioPharma announces advances in mucosal vaccines for botulinum toxin
Breast Cancer - Neoprobe completes regulatory submission for Lymphoseek for breast and skin cancer biopsies
Business Update - Celera Genomics announces sale of therapeutic programs to Pharmacyclics
Business Update - Demand for Medical Services' Dengue Fever rapid test kit heats up
Business Update - Genelabs announces receipt of notice from Nasdaq, drug development restructuring
Campylobacter - Signal transduction in epithelial cell invasion by Campylobacter is examined
Cancer Research - Reata announces RTA 402 entering clinical development as promising oral anticancer drug
Cancer Therapy - U.S. FDA grants 510(k) clearance for implantable radiation sensor for treating cancer
Cervical Cancer - Cervical cancer linked to expression of FasL
Chickenpox Vaccine - Routine varicella vaccination should be implemented in Saudi Arabia
Clinical Trials - Chiron announces initiation of Phase 1 trial for CHIR-265 in melanoma
Clinical Trials - Corautus announces termination of patient enrollment in GENASIS severe angina clinical trial
Clinical Trials - Cortex updates progress on clinical hold of AMPAKINE CX717
Clinical Trials - Emisphere completes enrollment for Phase II oral insulin clinical trial
Clinical Trials - Labopharm reports positive results for phase 3 study of once-daily pain medication tramadol
Collaborations - Forest and Almirall announce a collaboration agreement on new therapy for COPD
Colon Cancer - MoviPrep receives U.S. FDA approval letter
DPT Vaccine - Costs of scaling up vaccination in poor countries are examined
Dengue Fever - Recent studies from France, Brazil and the United States add new data to dengue fever research
Diabetes Type 2 - Depomed data published on Glumetza, an FDA-approved treatment for type 2 diabetes
Diabetic Peripheral Neuropathy - Quigley to commence human testing of QR-333 topical diabetic peripheral neuropathy new drug
Drug Delivery - Non-oral methylphenidate transdermal patch system for ADHD approved by U.S. FDA
Drug Development - Aldagen IND for stem cell trial to treat critical limb ischemia is cleared by U.S. FDA
Drug Development - American Pharmaceutical Partners receives U.S. FDA approval for Mitoxantrone
Drug Development - Cellegy's licensee for Tostrex in Europe has reported successful conclusion of E.U. MRP process
Drug Development - MGI Pharma submits NDA to U.S. FDA on oral glutamine for treating oral mucositis
Drug Resistance - Multidrug resistance in cancer targeted with newly developed drugs
Ebola Virus Vaccine - cAdVax-based bivalent Ebola vaccine induces immunity against Sudan and Zaire Ebola species
Ebola Virus Vaccine - Chimpanzee adenovirus vaccine protects against Zaire Ebola virus
Environmental Health - Method to measure urinary monohydroxy metabolites of polycyclic aromatic hydrocarbons is developed
Epidemiology - Canine visceral leishmaniasis in United States and Canada is focus of review
Epidemiology - Improved measles surveillance in Cameroon reveals two dynamic patterns of incidence
Epidemiology - Influenza pandemic planning is reviewed
Finance - DOR BioPharma announces private equity financing of $3.65 million
Finance - Fred Hutchinson Cancer Research Center receives boost from Susan G. Komen Foundation
Food Safety - Antibiotic-resistant Salmonella isolated from imported foods is characterized
Food Safety - PCR methods to measure Salmonella in homemade ice cream compared
Food Safety - Tissue-fluid correlations were used to estimate gentamicin in steer kidneys
Food-Borne Illness - Multidrug-resistant Salmonella outbreak linked to ground beef at school potluck
Forensic Science - GHB free-acid solution formation studies and characterization reported
Forensic Science - Isolation and spectroscopy characterization of gamma-hydroxybutyric acid is reported
HIV/AIDS - Data from Germany, the United States and Belgium advance knowledge in HIV/AIDS research
HIV/AIDS - Recent findings in HIV/AIDS described by researchers from the United Kingdom, Mexico and Spain
HIV/AIDS - Recent studies from the United States and Spain add new data to HIV/AIDS research
HIV/AIDS - Researchers' work from the United States and South Africa adds to HIV/AIDS body of knowledge
HIV/AIDS Diagnosis - HIV-infected adolescents unlikely to initiate HIV testing
HIV/AIDS Diagnosis - Increased HIV testing among young men who have sex with men is needed
HIV/AIDS Education - Conference to address significant impact of HIV/AIDS on Native Americans
HIV/AIDS Pathogenesis - CD4+ T cell depletion correlates with peak viral load in SHIV infection
HIV/AIDS Risk Factors - Methamphetamine use and associated risk of HIV/STD infection were focus of national consultation
HIV/AIDS Vaccine - Robust HIV-specific immune responses were induced by DNA vaccine plus vaccinia virus boost
HIV/Tuberculosis Epidemiology - HIV infection is driving tuberculosis epidemic in periurban South African community
Healthcare Coverage - Centers for Medicare and Medicaid Services (CMS) advises Niaspan is now Part D-eligible
Hepatitis B Virus - Studies from the United States and Canada describe new findings in hepatitis B virus research
High Cholesterol - National Lipid Association statin study shows liver monitoring is unnecessary
Imaging - U.S. FDA grants clearance to new PACS functions for diagnosing scanned cardiac images
Infectious Diseases - U.S. FDA alerts professionals of eye infections related to soft contact lens, solutions use
Influenza Vaccine - DelSite Biotechnologies presents data on innovative influenza vaccine
Influenza Vaccine - GEN ID Lab Services Inc. to clone entire H5N1 influenza virus genome to develop new vaccines
Influenza Vaccine - Influenza vaccine shortage did not affect pattern of vaccine-seeking behavior
Kawasaki Syndrome - Link between Kawasaki syndrome and coronary artery abnormalities was investigated
Lung Cancer Therapy - Genentech moves on Avastin with chemotherapy for nonsquamous, non-small-cell lung cancer
Malaria Therapy - Mefloquine induces dose-related neurological effects in rat model
Malaria Vaccine - Cellular reactivity to Plasmodium falciparum protein trap in Kenyans was examined
Marketing - U.S. FDA awards contract to assess postmarketing study commitment decision-making process
Measles Virus - Quantitative real-time RT-PCR assays to detect measles virus have been developed
Medical Devices - AerovectRx receives U.S. FDA 510(k) clearance for nebulizer drug delivery system
Medical Devices - Ellex receives FDA 510(k) clearance for industry's first solid-state red/green photocoagulator
Medical Devices - Medtronic receives FDA approval for insulin pump with real-time continuous glucose monitoring
Medical Devices - Medwave deploys 3D interactivity enabling online demonstration of blood pressure measuring device
Medical Devices - NxStage Medical receives FDA clearance of novel device to prepare high purity dialysate at home
Medical Statistics - One-shot estimate of multiple readers and multiple cases variance has been developed
Meningitis - Meningococcal disease mortality in U.S. for 1990-2002 is reported
Mental Health - HIV/AIDS stigma adversely affects mental health of HIV-positive men
Mergers & Acquisitions - Cellegy reports sale of Cellegy Australia to Epsilon Pharmaceuticals
Multiple Myeloma - Revlimid marketing authorization application accepted by EMEA for review
Myocardial Infarction - Diabetes-related myocardial infarction is increasing in New York City
Obesity - Recent studies from the United States add new data to obesity research
Obesity Epidemiology - Public housing developments have limited access to physical activity or healthy food resources
Obstetrics - Obstetricians and radiologists express concerns about nonmedical fetal ultrasound
Ophthalmology - Federal agencies investigate soft contact lens use, solution as cause of serious eye fungus
Ophthalmology - Fusarium keratitis infection may put soft contact lens wearers at risk
Orthopedics - Adverse events related to autologous chondrocytes are summarized
Otitis Media - Specialists try to speed up cure for ear infections
Ovarian Cancer - Up-regulation of VEGF and induction of MMP-2 enhance ovarian cancer invasiveness
Pain Management - Neuroscience Therapy Corp. receives FDA approval to begin marketing P-Stim in U.S.
Patents - VISICU notified patent office to allow amended claims of eICU patent after re-examination
Patient Safety - U.S. FDA proposal seeks to prevent deaths and injuries from medical gas mix-ups, contamination
Pediatric Vaccines - $1.5 billion needed to ensure 12-month stockpile of pediatric vaccines
Pediatrics - Reports from the United States add new data to pediatrics research
Personnel - Devon Medical Supplies announces John Iona as new president
Personnel - Invitrogen names NIH stem cell scientist Mahendra Rao, MD, PhD, to lead new research area
Pertussis Prevention - Vaccinating health care workers against pertussis is cost effective
Pneumococcal - Research from the United States and United Kingdom add new data to pneumococcal body of knowledge
Public Health - Violence prevention agenda is established at U.S. CDC
Rabies Virus - Incidence of rabies post-exposure prophylaxis in South Carolina is higher than estimated
Respiratory Syncytial Virus - Rule to predict hospitalization risk for respiratory syncytial virus infection is developed
SARS - Research from Austria, Taiwan and the People's Republic of China in SARS provides new insights
SARS Vaccine - SARS vaccine development is focus of review
Salmonellosis - Method enables effective supplementation for isolation of Salmonella enteritidis in egg white
Sexually Transmitted Disease - Self-esteem and emotional distress affect sexual behavior differently in adolescent females
Sinusitis - U.S. FDA grants Accentia Biopharmaceuticals Fast Track status for SinuNase
Smallpox Vaccine - Smallpox vaccines were efficacious after exposure to temperatures not recommended for shipping
Streptococcus Pneumoniae - Proteomic analysis of Streptococcus pneumoniae reveals new protein relationships
Suicide - Integrated approach helps prevent suicide and youth violence
Surgical Technology - Atrium Medical receives U.S. FDA approval for C-QUR coated mesh
Surgical Technology - U.S. FDA clears Medtronic Performer Cardiopulmonary Bypass System heart-lung machine
Tuberculosis - Improved programs are associated with decreasing TB incidence in U.S.
Tuberculosis - Researchers' data from Canada and the United States advance tuberculosis research
Tuberculosis - Researchers' work from the United States adds to tuberculosis body of knowledge
Tuberculosis - Risk of active TB among schoolchildren in Hong Kong is reported
Tuberculosis Vaccine - Mycobacterium bovis BCG expressing SIV Gag protein induces immune responses
Vaccines - Reports from Netherlands and United States advance knowledge in vaccines research
Vaccines - Reports from the United States add new data to vaccines research
Vaccines - Research from the United States and United Kingdom add new data to vaccines body of knowledge
Vaccines - Researchers from the United States and Ireland describe findings in vaccines studies
Vaccines - Studies from the United States and United Kingdom describe new findings in vaccines research
Vaccinia Virus Vaccine - Vaccinia virus mutated in envelope proteins A33R and B5R are immunogenic
Virology - Chimeric SIN/VEE viruses clear Venezuelan equine encephalitis virus from brain
Virology - PKR activity is modulated in cells infected by bovine viral diarrhea virus
Virology - Some porcine endogenous retroviruses can infect human cells
West Nile Virus - Rapid assay to measure West Nile virus neutralization has been developed
West Nile Virus Vaccine - West Nile virus vaccination is currently not cost effective
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