Published in Medical Letter on the CDC and FDA, May 10th, 2006
Study 1: Researchers characterize a vaccinia virus mutant with a deletion of the D10R gene encoding a putative negative regulator of gene expression in a recent issue of the Journal of Virology.
According top their report, "The D9 and D10 proteins of vaccinia virus are 25% identical to each other, contain a mutT motif characteristic of nudix hydrolases, and are conserved in all sequenced poxviruses. Previous studies indicated that overexpression of D10 and, to a lesser extent, D9 decreased the levels of capped mRNAs and their translation products. We...
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