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Vaccines

Studies from the United States and United Kingdom describe new findings in vaccines research

Published in Medical Letter on the CDC and FDA, May 10th, 2006

Investigators in the United States and United Kingdom have published new vaccines data.

Study 1: Researchers characterize a vaccinia virus mutant with a deletion of the D10R gene encoding a putative negative regulator of gene expression in a recent issue of the Journal of Virology.

According top their report, "The D9 and D10 proteins of vaccinia virus are 25% identical to each other, contain a mutT motif characteristic of nudix hydrolases, and are conserved in all sequenced poxviruses. Previous studies indicated that overexpression of D10 and, to a lesser extent, D9 decreased the levels of capped mRNAs and their translation products. We...

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