Susan Hasty, Publisher
Table of Contents . . . May 17th, 2006
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Medical Letter on the CDC and FDA | Other Publications
Allergy & Immunology - Competition ELISA is sensitive for detection of small allergen quantities
Epidemiology - Analysis of deaths with unknown cause in mortality analyses is discussed
Food-Borne Illness - Analyzing Campylobacter species on turkey farms benefits from multiple typing methods
Stroke - Preeclampsia increases risk of ischemic stroke among young women
Tuberculosis - Public-private collaborations can improve tuberculosis control in India
Adverse Drug Reaction - Adverse events after hepatitis A/B combination vaccine reported
Angiology - Lymphangiogenesis occurs with hemangiogenesis via vascular splitting
Anthrax Vaccine - Recombinant Bacillus anthracis protective antigen protects against inhalational challenge
Asthma - First patient in U.S. is treated with Asthmatx' investigational outpatient procedure
Autoimmune Diseases - Theiler virus infection induces astrocyte recognition by autoreactive T cells
Avian Influenza - Aquatic birds, not cats, play role in spread of H5N1 Asian strain of avian flu, WHO says
Avian Influenza - GEN ID Lab Services, Inc. to identify molecules for treating human infections of avian flu
Blood Safety - Gen-Probe applies to use PROCLEIX TIGRIS System to screen donated blood for West Nile virus
Blood Safety - West Nile virus targets monocytes-macrophages after blood transfusion
Bovine Tuberculosis Vaccine - Mycobacterial vaccine is more potent than BCG against bovine tuberculosis
Breast Cancer - North American Scientific announces U.S. FDA clearance of low-dose breast brachytherapy product
Breast Cancer - RANKL regulates cancer cell migration and bone metastasis
Business & Finance - Endo Pharmaceuticals reports net sales of $205 million in first quarter
Business & Finance - Enpath Medical reports 42% increase in first quarter sales
Business Update - Amitiza launches in U.S. to treat chronic idiopathic constipation
Business Update - Speedel, Phase I and II developer of hypertension drug, announces Novartis NDA accepted
Cancer Gene Therapy - Cervical cancer HPV16 oncogene silencing is affected by RNA interference
Cancer Research - Lilly comments on results of tamoxifen and raloxifene cancer study reported by NSABP
Cancer Therapy - Intravenously administered vitamin C proposed as cancer therapy
Cancer Treatment - New findings from the United States, People's Republic of China and France in the area of cancer treatment detailed
Cardiovascular Disease - Two approaches to coronary risk assessment are discussed
Cardiovascular Research - Looming chronic disease plus infectious disease epidemics creates a double burden in Africa
Childhood Obesity - Predictors of overweight at the age of 4.5 years have been determined
Cholera Vaccine - Cholera vaccine candidate IEM108 resists CTX Phi infection
Clinical Trials - GenoMed to offer free clinical trial for mumps
Clinical Trials - U.S. FDA approves further changes to CORTOSS IDE pivotal study protocol
Complementary & Alternative Medicine - Immunogenicity is enhanced by Chinese herbal medicinal ingredients
Diagnostics - DOBI Medical's ComfortScan system granted approval in the Russian Federation
Diagnostics - Evidence is deficient for efficacy of bleach microscopy for TB case detection
Diet & Nutrition - Mossbauer spectroscopy was applied to determine iron state in ferrous-iron-containing supplements
Drug Development - Alkermes, Cephalon receive U.S. FDA approval for Vivitrol to treat alcohol dependence
Drug Development - Antares announces U.S. FDA acceptance of NDA for transdermal estradiol gel
Drug Development - Baxter announces new Aviva line of intravenous solutions
Drug Development - FermaVir announces U.S. FDA supports proceeding with clinical study of antiviral for shingles
Drug Safety - Shire receives interim response from U.S. FDA on Adderall XR citizen petition
Epidemiology - Live shigellosis clusters identified by prospective space-time scan statistics
Epidemiology - Malawian children are 5 times more likely to die of bacterial meningitis than English children
Epidemiology - Parents with atopic family history may adopt 'prudent' lifestyle for their infant
Facilities - Novavax successfully completes renovation and validation for cGMP compliance for Maryland facility
Food-Borne Illness - Staphylococcal enterotoxin B quantification in food matrixes by LC-MS method is developed
Genetics - New findings from the United States, Taiwan and Japan in the area of genetics detailed
Genetics - Researchers from the United States, France and Canada describe findings in genetics studies
Genetics & Genomics - Press coverage of genomics in Quebec are focus of review
Genetics & Genomics - Tm Bioscience signs Turkey distributor for RVP to detect avian flu virus, many others
HIV Genetics - HIV envelopes induce distinct gene expression profiles in blood mononuclear cells
HIV/AIDS - Reports from Switzerland, the United States and France add new data to HIV/AIDS research
HIV/AIDS - Reports from the United States and Italy describe recent advances in HIV/AIDS research
HIV/AIDS Therapy - Amino acid insertions of HIV-1 protease interfere with virus replication
HIV/AIDS Therapy - U.S. FDA grants fast track status to tramadol ER to treat HIV-associated neuropathy
HIV/AIDS Vaccine - HIV clade C immunization by DNA prime/protein boost was safe and immunogenic in mice
HIV/AIDS Vaccine - HIV-1 control is affected by escape mutations in p24 Gag
HIV/AIDS Vaccine - HIV-1 subtype C vaccine candidate for India has been developed
HIV/AIDS Vaccine - HIV-1 Tat protein plus lipopeptide adjuvant elicited systemic and mucosal immune responses
Hepatitis C Virus - Hepatitis C virus NS5A protein is involved in apoptosis and infectivity
High Blood Pressure - U.S. FDA to review new drug application for Rasilez to treat high blood pressure
Human Herpesvirus-8 Infection - HHV-8 infection control influenced by common variants in key host immune genes
Infection Control - Ultrasonic nebulizers should be disinfected at least once daily
Influenza - Researchers' data from the United States and Canada advance influenza research
Influenza - Researchers' work from the United States and Norway adds to influenza body of knowledge
Influenza Vaccine - Age-related changes were found in immune response to influenza vaccine in elderly adults
Influenza Vaccine - Anti-influenza responses produced by DNA chimeric molecule are long-lasting
Influenza Vaccine - Impact of corticosteroids on immune response to influenza vaccine is examined
Influenza Vaccine - Influenza hemagglutinin is purified and expressed
Information Technology - BrainLAB iPlan Flow software opens new avenues for delivering drugs to the brain
Labor Monitoring - U.S. FDA provides LMS Medical Systems clearance for standalone offering of CALM Curve
Leishmaniasis Vaccine - DNA vaccine effective against visceral leishmaniasis in dogs
Leishmaniasis Vaccine - Leishmaniasis immunity is conferred by IL-12 DNA with rORFF antigen
Leishmaniasis Vaccine - Leishmaniasis vaccine candidates were screened
Liver Function - Telithromycin can cause severe hepatotoxicity
Malaria - Researchers from the United States and Colombia describe findings in malaria studies
Malaria Vaccine - Plasmodium falciparum merozoite surface protein-142 shows promise as vaccine candidate
Malaria Vaccine - Plasmodium yoelii selectable markers have been developed
Malaria Vaccine - Clinical immunity to malaria is focus of review
Malaria Vaccine - Immune response to pre-erythrocytic stages of malaria parasites is focus of review
Medical Devices - Ascent Healthcare receives 510(k) clearance for DePuy ACE external fixation devices
Medical Devices - Studies show increased rate of suicide in women with silicone breast implants
Medical Devices - U.S. FDA approves programmer for implantable cardioverter defibrillators, pacemakers
Medical Devices - U.S. FDA grants 510(k) clearance for image analysis system used with Ki-67 stained tissues
Meningitis Vaccine - Neisseria meningitidis vaccine's weak immunogenicity is overcome by prime-boost strategy
Meningococcal Vaccine - Neisseria meningitidis outer membrane vesicles prevent bacteremia
Meningococcal Vaccine - Antibody responses to meningococcal vaccines were focus of randomized trial
Mumps Vaccine - Leningrad-3 live mumps vaccine virus can be transmitted horizontally
Mumps Vaccine - Monotypic immune responses to different mumps virus strains found
Ophthalmology - Doctors of optometry support Bausch & Lomb's solution recall, urge users to stop using
Osteoporosis - Methods to improve compliance with bisphosphonate therapy for osteoporosis outlined
Pediatric Vaccine - Vaccination information leaflets are useful for parents
Pertussis Vaccine - Single dose of acellular pertussis vaccine was effective in nonvaccinated adolescents
Pharmacology - Bioavailability of two losartan formulations is equivalent
Pharmacology - Pharmacokinetics of liquid versus tablet buprenorphine reported
Phenylketonuria - Phenylketonuria was corrected by vector-mediated gene transfer in mouse model
Plague - Findings from the United States advance knowledge in plague research
Plague Transmission - Pneumonic plague transmitted by respiratory droplets not aerosols
Polio Vaccine - Poliovirus replicative fitness is modulated by deoptimization of synonymous codon usage in capsid
Prison Health - MRSA outbreak among prison inmates associated with low personal hygiene
Product Licensing - Purdue researchers report progress on compounds that may prevent neural cell death
Public Health - Haemophilus type b plus DPT vaccine (DTP-Hib) is cost-effective in Indonesian infants
Quality Assurance - Best Practices offers toolkit for improving quality assurance in pharma industry
Rabies - Researchers from the United States and India describe findings in rabies studies
Rabies Diagnosis - Rabies antibody is quantified by chicken-embryo-related cell line
Renal Anemia - Roche submits application to U.S. FDA to market C.E.R.A. for renal anemia
Sexual & Reproductive Health - Unprotected sex with multiple partners more likely after drinking alcohol
Shigellosis Vaccine - Shigella flexneri 2a and S. sonnei bivalent invasin complex vaccine is developed
Tuberculosis - Findings from Switzerland, the United States and France advance knowledge in tuberculosis research
Tuberculosis - Research from the United States and People's Republic of China add new data to tuberculosis body of knowledge
Tuberculosis Screening - Symptom-based screening identifies 91% of children with intrathoracic tuberculosis
Tuberculosis Vaccine - Mycobacterium tuberculosis mce-2 and mce-3 mutants increase immunogenicity of live vaccines
Tuberculosis Vaccine - TB epitope immunity is elicited by dendritic cell vaccine
Type 1 Diabetes - Type 1 diabetics on inhaled insulin show positive results in phase 2 clinical trial
U.S. Food & Drug Administration - Study assesses relationship between conflicts of interest and voting patterns at U.S. FDA meetings
Vaccine Development - Microencapsulated foot-and-mouth disease DNA vaccine enhances immunogenicity
Vaccine Safety - Anaphylaxis after vaccination due to gelatin hypersensitivity has been reported
Vaccines - Data from the United States, China and France advance knowledge in vaccines research
Vaccines - Studies from Taiwan and the United States advance knowledge in vaccines research
Vascular Disease - Schering-Plough gets Fast Track designation for thrombin receptor antagonist SCH 530348
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