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Medical Letter on the CDC and FDA

Susan Hasty, Publisher

Table of Contents . . . May 24th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Medical Letter on the CDC and FDA | Other Publications

Environmental Health - Lead exposure increases risk of low birth weight in Idaho

HIV/AIDS Epidemiology - Current trends in Rwanda's HIV/AIDS epidemic reviewed

Legionellosis - Monochloramine may reduce Legionella colonization of water systems

Pediatric Vaccine - DTaP and MMR shortages impact timeliness of child vaccination coverage

Pneumococcal Vaccine - Pneumococcal vaccine reduces rate of drug-resistant Streptococcus pneumoniae infections

Adenoviral Vector - Replication properties of human adenovirus in different animal species described

Antioxidants - Gamma-irradiation reduces antioxidant activity of black pepper

Antipsychotics - Delusions of parasitosis treated successfully with olanzapine

Business & Finance - Celgene Corporation reports record revenue and operating profits

Business Update - Advancis Pharmaceutical provides update on additional Keflex products

Business Update - St. Francis Medical launches nonfusion treatment for common degenerative spine disorder

Cancer Therapy - Reaction of geldanamycin analogues with glutathione produces potential anticancer agents

Cancer Therapy - Symposium held in U.S. to discuss research on liver-directed radiotherapy with microspheres

Cell Regulation - Nitric oxide gradients influence chemotaxis of endothelial cells

Chlamydia Therapy - Most clinicians adhere to U.S. CDC guidelines for chlamydia treatment

Cholera Vaccine - Proteome analysis of sorbitol fermentation-specific protein in Vibrio cholerae performed

Clinical Trials - U.S. FDA approves large reduction in size of WorldHeart RELIANT clinical trial design

Clonorchiasis Vaccine - DNA encoding cysteine proteinase protects against clonorchiasis

Collaborations - Colgate-Palmolive Company announces partnership to eliminate dental decay in children

Coronavirus Vaccine - Neurovirulent human coronavirus recovered from infectious cDNA clone

Cytomegalovirus Transmission - Cytomegalovirus infection transmission in infants via breast milk reviewed

Dengue Virus Vaccine - Polytopic vaccination modifies immunological response to dengue fever

Developmental Biology - Lens fiber cell disintegration is associated with crystallin loss

Diabetes - Researchers from the United States and United Kingdom report recent findings in diabetes

Diabetes Therapy - Incretin hormones being developed for type 2 diabetes treatment

Diagnostics - U.S. FDA approves mobile configuration of digital mammography system

Diet & Nutrition - Dietary supplements and related products summarized

Diet & Nutrition - Proposed rule on good manufacturing practice in dietary supplements reviewed

Diet & Nutrition - Strategies to optimize vitamin D status in special needs populations presented

Drug Development - Akorn announces supplemental new drug application approval for Inapsine

Drug Development - Alfacell provides update on onconase phase IIIb trial

Drug Development - Amicus Therapeutics files investigational new drug application for AT2101 for Gaucher disease

Drug Development - Astex Therapeutics reports IND approval for cancer drug AT9283

Drug Development - Cellegy announces results of the U.S. FDA's Cardio-Renal Advisory Committee meeting

Drug Development - Cephalon, Inc. provides update on regulatory status of SPARLON

Drug Development - Novartis' NDA for high blood pressure treatment accepted for review by U.S. FDA

Drug Development - U.S. FDA grants Orphan Drug designation to Nexavar for treatment of liver cancer

Drug Development - U.S. FDA requests more information related to Hexvix NDA

Emergency Medicine - Chitosan-based hemostatic dressing performs well in combat operations

Environmental - Reports from the United States and Japan advance knowledge in environmental research

Enzymology - Data from the United States advance knowledge in enzymology research

Facilities - Panacea Biotec inaugurates pharmaceutical formulation plant at Baddi

Finance - MGI Pharma reports Q1 2006 revenues of $78.2 million compared to $63.2 million in Q1 2005

Generic Drugs - Taro receives tentative ANDA approvals for carvedilol tablets, ondansetron HCL tablets

Generic Drugs - U.S. FDA grants approval for Teva's generic pravastatin, court denies Apotex's injunction

HIV/AIDS - Researchers from Italy, the United Kingdom and the United States report details of new studies and findings in the area of HIV/AIDS

HIV/AIDS - Researchers' findings from the United States advance HIV/AIDS research

HIV/AIDS Epidemiology - HIV/AIDS epidemic in Ethiopia expanding in rural areas

Hepatitis C Therapy - Novelos Therapeutics IND for novel hepatitis C drug accepted by U.S. FDA

Hepatitis C Virus - Chronic HCV infection risks for steatosis and progression of fibrosis clarified

Hypertension - New findings from the United States and Canada in the area of hypertension described

Influenza - Researchers' findings from New Zealand, United Kingdom and United States advance influenza research

Influenza A Vaccine - Inactivated subvirion influenza A vaccine appears immunogenic

Influenza Vaccine - Influenza vaccination cost-effective in elderly adults

Influenza Vaccine - Influenza vaccination coverage in German adults unsatisfactory

Influenza Vaccine - Influenza vaccine effectiveness low among non-institutionalized elderly in Japan

Influenza Vaccine - Interventions increase influenza vaccination of children in inner-city health centers

Influenza Vaccine - Intramuscular injection required to optimize influenza vaccination in elderly

Influenza Vaccine - Neuraminidase enhances effect of influenza virus vaccine

Information Technology - U.S. FDA advances federal e-health effort

Japanese Encephalitis Vaccine - Single dose of Japanese encephalitis vaccine provides protection

Leishmaniasis Vaccine -  Leishmania infantum cysteine proteinases protect against visceral leishmaniasis

Leishmaniasis Vaccine - Divergent portion of Leishmania protein protects against Leishmania major

Leishmaniasis Vaccine - Escheriosome-entrapped antigens protect against visceral leishmaniasis

Leishmaniasis Vaccine - Leishmune against visceral leishmaniasis is transmission-blocking vaccine

Leishmaniasis Vaccine - Vaccine based on cysteine peptidases and IL-12 does not protect against leishmaniasis

Leukemia - Researchers from the United States and Italy detail new studies and findings in the area of leukemia

Lyme Disease - Economic impact of Lyme disease investigated

Lyme Disease Vaccine - Oral vaccine reduces Borrelia burgdorferi carriage and protects against Lyme disease

Malaria Vaccine -  Plasmodium falciparum malaria vaccine with CpG oligodeoxynucleotide is immunogenic

Malaria Vaccine - Malaria vaccine development reviewed

Measles Vaccine - Measles immunity and immunization status in Australian children reported

Medical Devices - Ascent Healthcare gets U.S. FDA OK to increase cycle count for reprocessed EP catheters

Medical Devices - Atrium Medical receives U.S. FDA approval for vascular implant technology

Medical Devices - Barrx Medical reports U.S. FDA clears system to treat Barrett esophagus

Medical Devices - Cardiac Science receives U.S. FDA 510(k) clearance for new electrocardiograph

Medical Devices - Cyberkinetics' Andara product regenerates nerves in chronic spinal cord injury model

Medical Devices - Endologix receives FDA marketing approval for short body/short limb variants of Powerlink-120 ELG

Mosquito-Borne Disease - Eliminating octenol enhances trapping of Japanese encephalitis virus mosquito vectors

Obesity Epidemiology - Body weight continues to increase in U.S. men and adolescents

Papillomavirus - Findings from the United States in papillomavirus provide new insights

Parainfluenza Vaccine - Attenuated and effective human parainfluenza virus type-1 vaccines developed

Parainfluenza Vaccine - Live parainfluenza type 3 virus vaccine in children reviewed

Pediatric Vaccine - Vaccine shortage inordinately affects vaccine coverage for American Indian/Alaska Native children

Pediatrics - 2000 U.S. CDC growth reference not appropriate for developing countries

Pelvic Organ Prolapse - Mentor receives U.S. FDA approval for NovaSilk synthetic mesh product for pelvic organ prolapse

Personnel - Ortec announces formation of stem cell and regenerative medicine scientific advisory board

Pertussis Vaccine - Combined DTPa-IPV vaccine safe and immunogenic in children

Plague Vaccine - Intranasal Protollin/F1-V vaccine protects against plague infection

Pneumococcal - Researchers' work from the United States and Greece adds to pneumococcal body of knowledge

Pneumococcal Vaccine - Pneumococcal vaccination efficacy unimpaired in HAART-treated HIV-infected patients

Preventive Medicine - Methods to measure resident physicians' preventive care discussed

Proteins - Research from the United States in proteins provides new insights

Public Health - Quality improvement needed at U.S. hospitals to improve inpatient vaccination rates

Renal Anemia - Roche submits application to U.S. FDA to market Cera for the treatment of renal anemia

Schistosomiasis Vaccine - Eosinophils help protect against schistosomiasis in HIV-infected patients

Sepsis Vaccine - Vaccine increases survival in Staphylococcus aureus sepsis model

Smallpox Vaccine - IMVAMUNE is promising candidate as third generation smallpox vaccine

Spontaneous Abortion - Intravenous immunoglobulin prevented recurrent pregnancy loss

Stem Cell Research - Cytori studies using adipose stem and regenerative cells in breast reconstruction

Surgical Technology - U.S. FDA grants 510(k) clearance for Kensey Nash's thrombectomy catheter system

Toxoplasmosis Epidemiology -  Toxoplasma gondii infection risk factors in Brazil outlined

Toxoplasmosis Vaccine -  Toxoplasma gondii RNA protects against toxoplasmosis

Tuberculosis Vaccine - Anti-mycobacterial Th1-cell responses does not enhance protection against tuberculosis

Tuberculosis Vaccine - Clonal response in Malawian subjects after BCG vaccine evolves over 12 months

Tuberculosis Vaccine - Lipid-encapsulated BCG induces long-term protection against tuberculosis

Vaccine Safety - Telephone inquiries help detect reactions to influenza vaccine in children

Vaccines - Findings from the United States and Israel advance knowledge in vaccines research

Vaccines - Recent studies from the United States, Germany and Russia add new data to vaccines research

Vaccines - Reports from the United States describe recent advances in vaccines research

Virology - Researchers from the United States and Brazil report details of new studies and findings in the area of virology

West Nile Virus - Commercial assays for detecting West Nile virus antigen compared

West Nile Virus - West Nile virus quantified in Culex species in southern U.S.

Wound Care - Sildenafil enhances skin flap survival in rats

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