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Medical Letter on the CDC and FDA

Susan Hasty, Publisher

Table of Contents . . . July 2nd, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Medical Letter on the CDC and FDA | Other Publications

Disease Control - Pediatric pneumococcal vaccination decreases adult Streptococcus pneumoniae

Drug Safety - Allometric methods to predict drug clearance in children are compared

Information Technology - Health survey estimates are impacted by substitution of cell phones for land lines

Osteoporosis - Effects of progestogen-only contraceptive drugs on bone mineral density are reviewed

Public Health - Delayed childbearing may contribute to trend in low birthweight rates

Adverse Drug Reaction - Clinical features of gemcitabine-associated lung injury are described

Adverse Drug Reaction - Severe serum sickness reaction to oral and intramuscular penicillin is reported

Allergy & Immunology - Inspire to begin phase II testing of intranasal epinastine for seasonal allergic rhinitis

Alzheimer Disease - Memory Pharmaceuticals delays initiation of phase IIa trial of MEM 3454 for Alzheimer disease

Anaphylactic Shock - Dextran 1 given before clinical dextrans reduces anaphylactic shock risk

Asthma - BioMarin, Alliant report U.S. Food and Drug Administration approval of Orapred ODT

Attention Deficit Hyperactivity Disorder - Shire announces significant ADHD symptom control reported with shorter Daytrana wear time

Avian Influenza - Report suggests companies need a more global, holistic preparation for potential avian flu epidemic

Avian Influenza Vaccine - DNA vaccine protects against avian influenza H9N2 virus challenge

Brucellosis Vaccine - Bioluminescent Brucella melitensis mutants confer protection

Business Update - Cera Products in demand for survival, disaster and avian flu preparedness kits

Cancer Gene Therapy - Chimeric promoter highly responsive to hypoxia and metals is identified

Cancer Therapy - Johnson & Johnson provides update on regulatory filing plans for Trabectedin

Cancer Therapy - Recent research demonstrates the effectiveness of Thal/Dex therapy in treating multiple myeloma

Candidemia Epidemiology -  Candida bloodstream infections decline in U.S. NICU patients

Cardiac Devices - Edwards Lifesciences completes 20th patient case in U.S. percutaneous heart valve feasibility trial

Cervical Cancer - Community outreach program boosts Pap tests among Vietnamese-American women

Childhood Cancer - Neuroblastoma in offspring linked to maternal use of recreational drugs

Clinical Trials - Coalition of Cancer Cooperative Groups features Lance Armstrong in Newsweek supplement

Dental Research - U.S. can improve access to dental care by studying other countries

Dental Water Contamination -  Legionella and free-living protozoa not reduced by flushing dental water lines

Developmental Biology - Hindbrain development requires a threshold level of Gbx2

Developmental Stuttering - Indevus reports promising phase II data for pagoclone in stuttering

Disease Control - Approach for influenza vaccination reduces disparity in minority community

Disease Control - Mothers' decision-making about vaccines for infants requires trust

Disease Control - U.N. Food and Agriculture Organization proposes plan to track bird migrations

Drug Abuse - Opioid addiction presents a major public health threat in Atlanta, Georgia

Drug Development - Corautus Genetics announces filing of response to U.S. Food and Drug Administration clinical hold

Drug Development - Lupin announces final U.S. Food and Drug Administration approval of Cefdinir Capsules

Drug Development - Regeneron receives fast-track designation for the IL-1 Trap in CIAS1-associated periodic syndromes

Drug Development - The U.S. Food and Drug Administration's reputation with the general public is under attack

Epidemiology - Asthma prevalence is elevated in U.S. Puerto Rican adults

Epidemiology - Sleeping sickness is spreading throughout southeastern Uganda

Erectile Dysfunction - Sildenafil improves self-esteem and confidence in men with erectile dysfunction

Finance - Corautus Genetics receives NASDAQ deficiency notice related to minimum bid price

Food-Borne Illness - Signal transduction mechanism in Clostridium superoxide anion generation is examined

Gastroenterology -  Campylobacter jejuni induces cytokine production in dendritic cells

Gene Research - Cytokeratin-associated protein in cancer was identified

Genetics & Genomics - Genetic screening of newborns by tandem mass spectrometry program effective

HIV/AIDS - Chembio participates in United Nations' High-Level Meetings on AIDS

Healthcare Costs - GPhA hails Omnitrope approval as significant step in opening door to consumer savings

Herpesvirus Research - Herpesvirus genes are differentially expressed in T cells and primary astrocytes

Human Papillomavirus Vaccine - Prophylactic human papillomavirus vaccines are focus of review

Hypertension - Debiopharm to initiate phase III trial for Sanvar in esophageal variceal bleeding

Hypertension - Teva receives tentative approval for generic Cozaar tablets

Imaging - Gender and body mass index affect ultrasound imaging of lateral abdominal muscles

Influenza Vaccine - Microbix's vaccine technology significantly boosts production of human flu virus from eggs

Influenza Vaccine - Trivalent influenza vaccine is safe among healthy young children

Influenza Virus Epidemiology - High influenza virus transmission allows rapid spread beyond local spatial constraints

Intravenous Immune Globulin - Current usage of intravenous immune globulin is subject of review

KSHV Vertical Transmission - Kaposi sarcoma-associated herpesvirus strains concordant between mother and child

Kidney Disease - Simvastatin improves sepsis-induced mortality and acute kidney injury

Legal Issues - Chimicles & Tikellis LLP issues update on securities class actions against Discovery Laboratories

Legal Issues - Federal District Court rules in landmark pharmacy compounding case

Lung Cancer - Point Therapeutics receives fast track designation for talabostat for non-small cell lung cancer

Malaria Therapy - Enantioselective LC/MS method to determine fenozan B07 in plasma has been developed

Market Analysis - Report of best practices shows private sector is moving toward universal access to HIV treatment

Medical Devices - American Bio Medica receives U.S. Food and Drug Administration clearance for its Rapid TOX

Medical Devices - Newer generation devices improve outcome of thoracic aortic stent grafting

Medical Devices - U.S. Food and Drug Administration clears Boston Scientific system for removing clots from arteries

Mental Health - Childhood headaches are linked to emotional and behavioral difficulties

Mycobacterium Ulcerans Drug Resistance - Antibiotics not effective against Mycobacterium ulcerans infection

Newborn Screening - Newborn screening recommendations of American Academy of Pediatrics are discussed

Occupational Exposure - Cancer incidence among pesticide applicators not linked to pendimethalin exposure

Orthopedic Devices - LDR Spine launches study for cervical artificial disc

Osteoporosis - Effects of combined hormonal contraception on bone mineral density are focus of review

Pain Management - ISTA begins phase III trials of a once-daily Xibrom for ocular pain and inflammation

Parasitology -  Taenia solium antigen diagnostic for cysticercosis characterized

Philanthropy - Elizabeth Taylor AIDS Foundation awards grant to AHF's South African AIDS Clinic

Prostate Cancer - Impact of prostate-specific antigen test for prostate cancer screening on decision-making assessed

Prostate Cancer - Prostate cancer risk not related to vitamin D receptor gene polymorphisms

Proteomics - Blue mesogleal protein of Cassiopea xamachana is trap for metals

Public Health - Enhancing communications improves quality of health care

Respiratory Medicine - Sepracor presents arformoterol data at American Thoracic Society International Conference

Rotavirus Vaccine - Intussusception after rotavirus vaccination remains unexplained

SARS Immunology - SARS coronavirus protein 7a interacts with hSGT

SARS Outbreaks - SARS apartment complex outbreak in Hong Kong spread primarily though the air

SARS Transmission - Nasopharyngeal shedding of SARS coronavirus is associated with genetic polymorphisms

Shingles Vaccine - FDA approves Zostavax, Merck's new vaccine for preventing shingles in adults 60 and older

Smallpox Vaccine - Intradermal immune response after infection with vaccinia virus is described

Stem Cell Research - AAM3100 mobilizes hematopoietic stem cells with long-term repopulating capacity

Surgical Technology - Smith & Nephew announces U.S. Food and Drug Administration approval of burn indication for Versajet

Thalassemia Therapy - Deferasirox and deferiprone are useful for iron overload in thalassemia major

Tobacco Use - Smokeless tobacco use has decreased among U.S. adolescents

Tuberculosis Healthcare Cost - Health departments incur substantial cost in managing suspect and noncounted tuberculosis

Tuberculosis Treatment - Time to sputum culture conversion is predictor of outcome in multidrug-resistant TB

West Nile Virus - Fatal hemorrhagic fever was caused by West Nile virus in United States

Anthrax - Reports from the United States and People's Republic of China describe recent advances in anthrax research

Bacterium - New findings from the United States, Germany and Vladivostok in the area of bacterium detailed

Blood Banks - Researchers from the United States detail new studies and findings in the area of blood banks

Cancer Treatment - Reports from the United States and Australia add new data to cancer treatment research

Cholera - Reports from the People's Republic of China, Netherlands and Bangladesh advance knowledge in cholera research

Epidemiology - Findings from the United States and Russia describe new data in epidemiology research

Epidemiology - New findings from the United States, Spain and Australia in the area of epidemiology detailed

Epidemiology - Studies from Netherlands, France and Australia describe new findings in epidemiology research

Genetics - Research from the United States add new data to genetics body of knowledge

HIV/AIDS - Findings from the United States advance knowledge in HIV/AIDS research

HIV/AIDS - Reports from South Africa and United States add new data to HIV/AIDS research

HIV/AIDS - Reports from the United States describe recent advances in HIV/AIDS research

HIV/AIDS - Researchers' findings from the United States and Brazil advance HIV/AIDS research

Herpes - Findings from Sweden and the United States in herpes provide new insights

Influenza - Findings from the United States and Australia advance knowledge in influenza research

Influenza - Reports from Bulgaria, the United Kingdom and the United States describe recent advances in influenza research

Influenza - Reports from the United States, Brazil and Switzerland add new data to influenza research

Influenza - Reports from the United States, Japan and New Zealand advance knowledge in influenza research

Influenza - Researchers from Russia and the United States report details of new studies and findings in the area of influenza

Leishmania - Data from India, Germany and the United Kingdom advance knowledge in leishmania research

Leishmania - Findings from the United States and Brazil advance knowledge in leishmania research

Leishmania - Recent findings from Iran, Brazil and the United Kingdom illuminate research in leishmania

Leishmania - Reports from Spain, Israel and Germany add new data to leishmania research

Lyme Disease - Researchers' work from the United States adds to lyme disease body of knowledge

Malaria - Recent studies from the United States, Australia and the Netherlands add new data to malaria research

Malaria - Researchers from the United States and India report details of new studies and findings in the area of malaria

Malaria - Researchers from Uganda, the United States and the United Kingdom provide details of new studies and findings in the area of malaria

Neurology - Reports from the United States add new data to neurology research

Obesity - New findings in obesity described from the United States, Hungary and Portugal

Obesity - Recent studies from the United States and United Kingdom add new data to obesity research

Osteoporosis - Reports from the United States advance knowledge in osteoporosis research

Papillomavirus - Researchers from the United Kingdom, Germany and France publish new studies and findings in the area of papillomavirus

Pertussis - Researchers from Belgium, Sweden and the United States describe findings in pertussis studies

Pneumococcal - Findings from Spain, Finland and Malawi describe new data in pneumococcal research

Prostate Cancer - New research from the United States and Australia in the area of prostate cancer detailed

Respiratory System - Findings from Netherlands, People's Republic of China and United Kingdom advance knowledge in respiratory system research

SARS - Researchers' findings from the People's Republic of China, Canada and the Netherlands advance SARS research

Streptococcus - Studies from the United States and Brazil add new findings to streptococcus body of knowledge

Tuberculosis - New research from the United Kingdom, Denmark and United States in the area of tuberculosis detailed

Vaccines - Findings from Israel, the United States and Germany describe new data in vaccines research

Vaccines - Researchers from South Africa and Australia report recent findings in vaccines

Vaccines - Researchers from the United States and Australia detail new studies and findings in the area of vaccines

Vaccines - Studies from the United States, Israel and Netherlands describe new findings in vaccines research

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