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Adverse Drug Reaction

Clinical features of gemcitabine-associated lung injury are described

Published in Medical Letter on the CDC and FDA, July 2nd, 2006

Investigators describe the clinical features and correlates of gemcitabine-associated lung injury in a recent issue of the journal Cancer.

According to their report, "Gemcitabine is a commonly used chemotherapeutic agent structurally and pharmacologically similar to cytarabine. Recently, instances of severe gemcitabine-associated lung injury have been reported. Herein, investigators affiliated with the Research on Adverse Drug Events and Reports (RADAR) pharmacovigilance program evaluated clinical characteristics of gemcitabine-associated severe acute lung injury from clinical trial reports, medical literature case reports, and spontaneous reports to the Food and...

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