Medical Letter on the CDC and FDA
Susan Hasty, Publisher
Table of Contents . . . July 9th, 2006
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Medical Letter on the CDC and FDA | Other Publications
Food-Borne Illness - Salmonella Heidelberg outbreaks in U.S. traced to poultry and eggs
Food-Borne Illness - Aging of cheese made from unpasteurized milk does not eliminate Escherichia coli O157:H7
HIV/AIDS Diagnosis - HIV RNA testing improves diagnosis of HIV infection in high-risk patients
Hepatitis E Virus - Locally acquired hepatitis E virus infection in Texas reported
Sexual & Reproductive Health - High-risk behaviors linked to Viagra use among men who have sex with men
Acute Myelogenous Leukemia - CuraGen and TopoTarget announce NCI-sponsored Phase II clinical trial with PXD101 for AML
Addiction Medicine - Cocaine abstinence in cocaine users appears to cause occult insomnia
Addiction Medicine - Method for self-administration of heroin, cocaine, and both under reinforcement in rats developed
Addiction Medicine - Mini-mental state exam for substance abuse research recruiting excludes small group of subjects
Addiction Medicine - Pain reduces psychosocial function during methadone treatment of opiate-dependence
Addiction Medicine - Psychiatric comorbidity poses challenge to public services for drug dependence
Addiction Medicine - Tachykinin NK3 receptor antagonist blocks behavioral effects of cocaine
Alcohol Use - Brief motivational interviewing is useful to curb excessive drinking
Alcohol Use - Daily naltrexone did not reduce daily drinking among women who abuse alcohol
Alcohol Use - Neuropeptide Y overexpression decreases ethanol self-administration in anxious rats
Alcohol Use - Suicide risk greater in alcohol-dependent subjects with personality disorders
Alcohol Use - Symptom checklist to screen for comorbid psychiatric disorders in alcoholism developed
Alcohol Use - Topiramate does not affect ethanol's rewarding affects
Alzheimer Disease - Isoflurane induces apoptosis and increases amyloid beta protein levels
Angiography - Virtual reality simulation can assess performance of carotid angiography
Anti-Emetics - Ondansetron more cost-effective anti-emetic than granisetron
Avian Influenza - Crucell announces large human clinical trial with bird flu vaccine
Avian Influenza - Tamiflu supply in Tijuana, Mexico, attracts bird flu-wary Americans, Medicine Store says
Blood Safety - Most countries fall short of ensuring a safe blood supply
Breast Cancer - Lilly concludes lower dose of Alimta in metastatic breast cancer suitable for further study
Business & Finance - Caraco Pharmaceutical Laboratories reports record sales for 4Q and full year 2006
Cancer Therapy - Ariad presents positive efficacy data on AP23573, an mTOR inhibitor
Cervical Cancer - Inventors praise U.S. Food and Drug Administration's approval of vaccine for cervical cancer
Chagas Disease - Galactose suppression in Trypanosoma epimastigotes changes cell morphology
Clinical Trials - Avanir reports safety update from ongoing study of Neurodex
Clinical Trials - Hollis-Eden gets U.S. Food and Drug Administration clearance to begin human studies of Neumune
Cognitive Science - Computers act as visual aids to enhance communication in therapy
Collaborations - Spectral, Toray Medical form therapeutic strategic alliance for severe sepsis management
Complementary & Alternative Medicine - Traditional Chinese medicines and bone formation reviewed
Depression Therapy - Self-report symptom scale for identifying depression remission validated
Depression Therapy - Transcranial magnetic stimulation for depression reviewed
Dermatology - Treatment of melasma reviewed
Diagnostics - Isotope ratio mass spectrometry used to detect doping with testosterone undecanoate
Diet & Nutrition - Low-phenylalanine diet in late-treated phenylketonuria improves behavior
Drug Development - Cardiome announces Refusal to File decision by U.S. Food and Drug Administration
Drug Development - Celator Pharmaceuticals presents positive results from Phase I study for CPX-1
Drug Development - Clavis Pharma's Elacyt enters Phase I/II clinical leukemia study
Drug Development - Cortex announces update on CX717 clinical hold
Drug Development - DNA microarray technology for target identification reviewed
Eating Disorders - Eating disorder therapy improves eating symptoms but not alexithymia and dissociation proneness
Eating Disorders - Video feedback improves relationship between bulimic mothers and their infants
Emergency Medicine - Prothrombin complex concentrate provides immediate reversal of warfarin
Emergency Medicine - VF incidence in pediatric cardiac arrest is greatest in children older than 12 years
Environmental Health - Automated solid-phase extraction method for measuring PAH metabolites developed
Environmental Health - Prenatal lead exposure reduces intellectual development in children
Epilepsy Therapy - Use of anti-epileptic drugs increasing in Denmark
Erectile Dysfunction - Tolerance to tadalafil does not occur during six months of treatment
Esophageal Cancer - Supratek reports positive phase 2 trial results of cytotoxic compound in esophagus cancer
Facilities - African Institute for Transfusion Medicine opened by Safe Blood for Africa Foundation
Finance - Novogen renegotiates Phenoxodiol license payment
Gastroenterology - Impact of aspirin and NSAID or cyclo-oxygenase-2-selective inhibitor on gastric ulcers examined
Generic Drugs - Lupin announces final U.S. Food and Drug Administration approval of Cefdinir for oral suspension
Generic Drugs - Perrigo announces participation in Dexcel's filing for generic version of Prilosec OTC
Generic Drugs - Ranbaxy receives approval to market doxycycline tablets
Headache & Migraine - Natural course of migraine attacks described
Healthcare Costs - Decentralized drug budgets increase physicians' awareness of drug costs
Hyperbilirubinemia - Pre-discharge newborn bilirubin screening reduces hyperbilirubinemia incidence
Hypertension - Older adults with hypertension receiving less aggressive therapy
Imaging - Repligen initiates clinical trial of Secretin for MRI imaging of the pancreas
Implants - Innovasis submits OpteryX cervical plate system for U.S. Food and Drug Administration clearance
Leishmaniasis Vaccine - Sodium antimony gluconate induces reactive oxygen species in Leishmania-infected macrophages
Leukemia - Interim darbepoetin alfa data suggest major response in treating anemia in MDS patients
Lipid Research - Dyslipidemia in Brazilian adults determined using hospital laboratory cohort
Lung Cancer - Tumor phenotype and tumorigenicity of lung carcinoma cells reversed
Lung Disease - Antimicrobial/elastase inhibitor elafin regulates lung dendritic cells
Malaria Therapy - Rectal quinine safe and effective for malaria treatment in children
Marburg Hemorrhagic Fever Vaccine - Replication-competent vaccine provides postexposure protection against Marburg virus
Measles Epidemiology - Confirmed cases of measles by region and age in U.S. reported
Medical Devices - Australian safety syringe gets clearance to market in the United States
Mental Health - Behavioral consequences of terrorism reviewed
Mental Health - Bipolar disorder patients affected by seasonal changes
Mental Health - Group intervention benefits female fire-setters with intellectual disabilities
Mental Health - Light therapy and fluoxetine effective for winter seasonal affective disorder
Mental Health - Study shows long-term treatment ineffective in patients with treatment-resistant depression
Mental Health - Symptoms of depression act as markers of bipolar II disorder
Mental Health - U.S. Food and Drug Administration approves the first drug for seasonal depression
Multiple Myeloma - Cytogen announces positive interim Phase I findings in QUADRAMET combination study
Multiple Sclerosis - IFN-beta for multiple sclerosis therapy increases stroke risk
Muscular Dystrophy - Mini-dystrophin/GFP fusion gene for studies of muscular dystrophy developed
Obsessive-Compulsive Disorder - Treatment-refractory obsessive-compulsive disorder reviewed
Osteoporosis - Vitamin D and bisphosphonates help prevent fractures in elderly adults
Pain Management - Botulinum toxin A is effective treatment for chronic low back pain
Pain Management - Neuropathic pain reduction correlates with improved quality of life
Pain Management - Self-report inventory to identify barriers to pain management developed
Pediatrics - Neonatal hemolysis due to maternal antibody to Rh antigen Cw reviewed
Pediatrics - One- and three-month leuprolide regimens in precocious puberty compared
Pemphigus Vulgaris - Aspreva, Roche receive orphan drug designation in U.S. for CellCept in pemphigus vulgaris
Personnel - Health Technology Center appoints Marc Larsen COO
Preventive Medicine - Women's health care maintenance visits offer opportunities for preventive care
Prostate Cancer - Dendreon publishes research showing promise of Provenge in combination with Avastin
Public Health - Strategies for using qualitative research in evidence-based public health practice reported
Respiratory Medicine - Antibiotics overused for adult upper respiratory infections in U.S.
SARS Therapy - Tertiary structure of SARS coronavirus helicase presented
Schizophrenia - Olanzapine offers benefits in Asian patients with schizophrenia
Sleeping Sickness - Sleeping sickness eliminated with intensive surveillance and treatment in Luba
Smallpox Vaccine - Electronic monitoring system to assess vaccination responses developed
Streptococcal Vaccine - Rhesus macaque model to assess Streptococcus pneumoniae vaccines developed
Stroke - 99mTc-HYNIC-annexin VSPECT imaging useful for monitoring stroke therapy
Suicide Risk Factors - Selective serotonin reuptake inhibitors increase suicide risk in elderly adults
Testosterone - Hypogonadal patients have impaired endothelial-dependent vasodilation
Trypanosomiasis Therapy - Melarsoprol inhibits thiamin uptake in neuroblastoma cells
Tuberculosis Pathogenesis - Polymeric IgR knockout mice more susceptible to mycobacteria
Type 2 Diabetes - Depomed publishes data on Glumetza/sulfonylurea glycemic control in type 2 diabetes
Allergies - Recent findings in allergies described by researchers from the United States, United Kingdom and Japan
Cancer Research - New findings from the United States, Japan and Australia in the area of cancer described
Cytomegalovirus - Researchers from the United States publish new studies and findings in the area of cytomegalovirus
Ebola - Findings from the United States describe new data in ebola research
HIV/AIDS - Findings from the United States and Belgium advance knowledge in HIV/AIDS research
HIV/AIDS - New findings from the United States, Australia and Italy in the area of HIV/AIDS detailed
HIV/AIDS - New findings in HIV/AIDS described from the United Kingdom, France and United States
HIV/AIDS - Researchers' work from Thailand, the United Kingdom and Argentina adds to HIV/AIDS body of knowledge
Heart Disease - Findings from the United States in heart disease provide new insights
Influenza - Data from Japan, the United States and Israel advance knowledge in influenza research
Influenza - Recent studies from the United States and Japan add new data to influenza research
Influenza - Researchers' findings from the United States and United Kingdom advance influenza research
Leishmania - Researchers from India and the United States describe findings in leishmania studies
Malaria - New data from the United States and Netherlands lluminates research in malaria
Measles - Research from Australia, Mexico and the United States add new data to measles body of knowledge
Measles - Studies from the United Kingdom and United States add new findings to measles body of knowledge
Meningitis - Reports from Cuba, the United Kingdom and Switzerland advance knowledge in meningitis research
Meningitis - Reports from France, Italy and the United Kingdom add new data to meningitis research
Polio - Recent findings in polio described by researchers from Nigeria, Japan and Brazil
Proteins - Studies from South Korea and United States add new findings to proteins body of knowledge
Rotavirus - Research from France and the United States add new data to rotavirus body of knowledge
Schizophrenia - New findings from the United States and Scotland in the area of schizophrenia detailed
Toxoplasmosis - New findings from France and the United States in the area of toxoplasmosis detailed
Tuberculosis - New findings from Canada, Japan and Kuwait in the area of tuberculosis detailed
Tuberculosis - Research from New Zealand, Switzerland and United States in tuberculosis provides new insights
Tuberculosis - Researchers from Japan, the United Kingdom and the United States report details of new studies and findings in the area of tuberculosis
Tuberculosis - Researchers from the United States, South Africa and United Kingdom publish new studies and findings in the area of tuberculosis
Tularemia - New data from the United States and Sweden lluminates research in tularemia
Vaccines - New findings from the United States in the area of vaccines detailed
Vaccines - Studies from Russia, Spain and the United States add new findings to vaccines body of knowledge
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