Neural Stem Cell Research
SDF1 alpha/CXCR4 signaling stimulates beta-catenin transcriptional activity in neural progenitors
Published in Medical Letter on the CDC and FDA, August 13th, 2006
"Stromal cell-derived factor (SDF-1), by activating its cognate receptor CXCR4, plays multiple roles in cell migration, proliferation and survival in the development of the central nervous system.
"Recently, we have shown that functional SDFla/CXCR4 signaling mediates chemotaxis through extracellular signal-regulated kinase (ERK) activation in the developing spinal cord," scientists writing in the journal Neuroscience Letters report.
According to Y. Luo and colleagues at the U.S. National Institute on...
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