Dengue Fever
Findings from the United States, France and Brazil in dengue fever provide new insights
Published in Medical Letter on the CDC and FDA, August 20th, 2006
Study 1: Tetravalent live attenuated dengue virus vaccination protected rhesus monkeys against dengue virus challenge.
According to a study from the United States, "Rhesus monkeys develop viremia after dengue virus (DENV) inoculation and have been used as an animal model to study DENV infection and DENV vaccine candidates. We evaluated, in this model, the protective efficacy of a live attenuated tetravalent DENV vaccine (TDV) candidate against parenteral challenge with parental near-wild-type DENV strains."
"Twenty monkeys were vaccinated...
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