Polio Vaccine
Long-term excretors of vaccine-derived poliovirus are reported
Published in Medical Letter on the CDC and FDA, August 20th, 2006
According to the report from England, "Seven cases of long-term poliovirus excretion in the U.K. and Ireland are reviewed in this paper. They include a rare case of long-term virus excretion by a healthy child recently found in Ireland and the case with the longest period of vaccine-derived poliovirus excretion by an immunodeficient individual ever known, 18 years."
"The evolution of viral properties such as antigenic structure, neurovirulence, sensitivity for growth at high temperatures, and differences in nucleotide sequence...
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