Medical Letter on the CDC and FDA

HIV/AIDS Pathogenesis - Genetic variation in chemokine gene cluster influences HIV-1 transmission and progression

HIV/AIDS Therapy - Aurobindo gets U.S. FDA approval for new drug application for HIV combination product

HIV/AIDS Vaccine - Antigenic diversity taxes efficacy of HIV vaccines based on consensus sequences

HIV/AIDS Vaccine - CytRx reports successful completion of Phase I HIV vaccine clinical trial

HIV/AIDS Vaccine - HIV gp120 expressing Gal alpha 1-3Ga1 beta 1-4GlcNAc-R epitopes has increased immunogenicity

HIV/AIDS Vaccine - HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells

Hospitals & Health Networks - INTEGRIS Southwest Medical Center adopts SurgiCount Safety-Sponge System for OR use

Influenza - Cold-adapted influenza virus vaccine does not produce illness in children

Influenza - Influenza vaccination is cost effective among elderly adults

Influenza - Refrigerator-stable formulation of FluMist for children 12-59 months submitted to U.S. FDA

Irritable Bowel Syndrome Therapy - Chinese herbal therapy was not effective for irritable bowel syndrome

Legal Issues - Repligen wins summary judgment against ImClone in Erbitux case

Leptospirosis Vaccine - Cytokine mRNA time course profiles in Leptospira-infected hamsters are presented

Leukemia - Proteasome inhibition is new treatment strategy in leukemia

Lipogenesis - Computational model is developed for energy metabolism during semistarvation and refeeding

Mental Health - Recent advances in optimizing electroconvulsive therapy are focus of review

Mental Health - Therapists' group attachments affect expectations of patients' group therapy attitudes

Neurodegenerative Disease - REM sleep behavior disorder is marker for neurodegenerative disorder

Non-small Cell Lung Cancer - Spectrum's partner initiates satraplatin trial with erlotinib in non-small cell lung cancer

Obesity Pathogenesis - Obesity is associated with taste, reward, and behavioral control brain abnormalities

Ophthalmology - Akorn receives U.S. FDA clearance to initiate trial for ocular anesthesia

Pain Management - Milnacipran shows potential for treating fibromyalgia pain

Panic Disorder - Barr receives approval for generic Xanax XR tablets for panic disorder

Parkinson Disease - Reasons for admission to hospital for Parkinson disease were examined

Parkinson Disease - Teva Neuroscience launches rasagiline compound as once-daily tablet for Parkinson disease

Pediatric Vaccine - Measles, mumps, rubella, and varicella combination vaccine is safe and immunogenic

Peripheral T Cell Lymphoma - Allos gets special protocol assessment for phase II study Antifolate PDX

Personnel - Steven Niedelman joins Quintiles Consulting as executive vice president

Pharmacology - Measurement of total gases is necessary to assess adequacy for dissolution testing

Pneumococcal Disease - Polysaccharide capsule plays key role in disease potential of Streptococcus

Pneumococcal Vaccine - 7-valent pneumococcal vaccine causes shift in causative sinusitis pathogens

Preventive Medicine - Priorities among effective clinical preventive services are reported

Rotavirus Epidemiology - Group B rotavirus infection is an important agent in childhood diarrhea

Salmonella Vaccine -  Salmonella in young chicks elicits circulating gammadelta T cells

Schistosomiasis Vaccine - Previous schistosome infections do not compromise efficacy of cercaria vaccine

Scoliosis Risk Factors - Joint laxity and gymnastics participation were linked in idiopathic scoliosis patients

Seborrheic Dermatitis - Barrier Therapeutics receives U.S. FDA approval of Xolegel gel to treat skin inflammation

Smallpox Vaccine - Generalized vaccinia is rare complication after smallpox vaccination

Streptococcal Vaccine - Antigen I/II family protein produced by group A Streptococcus is characterized

Surgical Technology - Innovasis submits PEEK Box System for U.S. Food and Drug Administration clearance

Tobacco Use - Repeated tobacco-use screening and intervention is cost effective

Tobacco Use - Varenicline was safe and effective for smoking cessation

Toxoplasmosis - Dihydroorotase from Toxoplasma gondii is characterized

Tuberculosis Epidemiology - Tuberculosis infectiousness of initial case associated with higher rate of cluster growth

Tuberculosis Research - Doctor knowledge about latent TB infection is low in areas with low TB incidence

Type 2 Diabetes - U.S. FDA accepts application for sitagliptin-metformin combination drug for type 2 diabetes

Type 2 Diabetes - U.S. FDA approves duetact (pioglitazone HCl and glimepiride) for treatment of type 2 diabetes

Vaccine Safety - No link found between developmental disorders and methylmercury exposure or MMR vaccine

Vector Development - Imidazole in loading buffer improves recovery of herpesvirus vectors

Yersiniosis Vaccine -  Yersinia enterocolitica invasin protein promotes MHC I- and II-restricted T cell responses

Alzheimer Disease - Researchers from the United States describe findings in Alzheimer disease studies

Anthrax - Recent findings from the United States illuminate research in anthrax

Depression - Researchers' data from Australia, France and the United States advance depression research

Diabetes - New research from the United States and Japan in the area of diabetes detailed

Gastroenterology - Researchers' work from the United States, Switzerland and Japan adds to gastroenterology body of knowledge

Hypertension - Researchers' work from Greece, the United Kingdom and Wales adds to hypertension body of knowledge

Leukemia - Researchers' findings from the United States and India advance leukemia research

Leukemia - Studies from the United States describe new findings in leukemia research

Malaria - Researchers from Laos, Switzerland and the United Kingdom report details of new studies and findings in the area of malaria

Meningitis - New findings from the United Kingdom and United States in the area of meningitis detailed

Neurology - Findings from the United States and France describe new data in neurology research

SARS - Findings from Italy, Taiwan and the United States describe new data in SARS research

Stroke - Reports from the United States and Switzerland advance knowledge in stroke research

Tuberculosis - Researchers' data from the United Kingdom and Brazil advance tuberculosis research

Vaccines - Recent studies from the United States and Netherlands add new data to vaccines research