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Type 2 Diabetes

U.S. FDA approves duetact (pioglitazone HCl and glimepiride) for treatment of type 2 diabetes

Published in Medical Letter on the CDC and FDA, September 3rd, 2006

Takeda Pharmaceuticals North America, Inc. (TPNA) announced that the U.S. Food and Drug Administration (FDA) has approved the New Drug Application (NDA) for duetact (pioglitazone HCl and glimepiride), pronounced "Duet Act," for the treatment of type 2 diabetes.

Duetact combines Actos(pioglitazone HCl) and glimepiride, two widely used diabetes medications with complementary actions, in a single tablet. Actos directly targets insulin resistance, a condition where the body does not efficiently use the insulin it produces; and glimepiride, a sulfonylurea, acts primarily by increasing the amount of insulin produced by the pancreas. These medications work in combination to...

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