Tetanus Therapy
Intrathecal tetanus vaccination is more effective than intramuscular route
Published in Medical Letter on the CDC and FDA, September 10th, 2006
According to a report from Rwanda, "Mortality caused by tetanus is still a serious health problem in developing countries. Apart from immunization, early treatment with equine anti-tetanus serum (ATS) or human tetanus immunoglobulin (TIG) is the real treatment that can avoid death."
"On pathophysiological grounds intrathecal administration would be preferred because of high concentrations of the antiserum in cerebrospinal fluid and thus around the nerve roots," said L. Kabura and collaborators...
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