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Malaria Therapy

Monthly sulfadoxine-pyrimethamine was effective against malaria in HIV-positive pregnant women

Published in Medical Letter on the CDC and FDA, September 24th, 2006

Monthly sulfadoxine-pyrimethamine intermittent preventive treatment was effective against malaria in HIV-positive pregnant women in Malawi.

According to a study from the United States and Malawi, "Intermittent preventive treatment during pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) decreases placental malaria parasitemia and associated maternal anemia, premature delivery, and low birth weight. However, the optimal regimen in the setting of a high prevalence of human immunodeficiency virus (HIV) infection remains unclear."

"In Malawi, where the efficacy of SP for the treatment of malaria in children is decreasing, we conducted a randomized,...

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