Published in Medical Letter on the CDC and FDA, September 24th, 2006
According to a study from the United States, "Cells exposed to simvastatin or to methyl-p-cyclodextrin show reduced poliovirus infection, without alteration in virus binding or on the kinetics of genome entry, suggesting that the steps which are altered are those post uncoating and genome entry. Reduction of infection by cyclodextrin is reversed by increasing MOI whereas that produced by simvastatin treatment is not, suggesting that the effects on infection are not due to a reduction in cholesterol."
"The differences in the...
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