Medical Letter on the CDC and FDA

Antimicrobial Resistance - Carbapenem resistance in Klebsiella is not detected by susceptibility testing

Food Safety - Infections associated with cantaloupe are growing public health concern

Meningitis Risk Factors - Invasive Enterobacter sakazakii disease in infants was examined

Meningitis Vaccine - Hib conjugate vaccine was effective in children in Kenya

Occupational Exposure - Workplace conditions frequently exacerbate asthma

Addiction Medicine - Drug treatment programs reduce criminal behavior

Advocacy - March of Dimes: Drug to prevent preterm birth needs prompt U.S. Food & Drug Administration approval

Alcohol Use - Social model alcohol recovery programs were examined as therapeutic landscapes

Anesthesia - Higher doses of ketamine are linked to increased intraocular pressure in anesthetized children

Antimicrobial Resistance - Daptomycin is active against all Gram-positive bacteria in Europe

Antimicrobial Resistance - Macrolide resistance in adults with pneumococcal pneumonia was examined for risk factors

Attention Deficit Hyperactivity Disorder - Shire announces new drug application for guanfacine extended-release for attention disorders

Bariatrics - High bariatric surgery complications rates suggest that improvements are needed

Biomedical Engineering - NeuroMetrix announces latest U.S. FDA 510(k) clearance for NC-stat system

Bipolar Disorder - Attention deficits in manic and euthymic patients with bipolar disorder were examined

Blood Safety - Stanford Blood Center testing all donated blood for West Nile virus

Blood Transfusion - Efficacy of shipped HLA-matched platelets is reported

Business Update - Akorn-Strides announces tenth new abbreviated drug application submission

Business Update - Atrium Medical receives U.S. FDA approval for the iVENA Vascular Patch

Business Update - Card Guard receives U.S. FDA 510(k) approval for ambulatory cardiac telemetry solution

Business Update - Cardinal Health suspends production of infusion pump following U.S. FDA actions

Business Update - Colazal pediatric exclusivity granted for bowel disease

Business Update - EPIX receives response from U.S. FDA regarding appeal of Vasovist Approvable Letters

Business Update - Mitek and StayinFront, Inc. partner to develop software for reducing drug diversion

Business Update - U.S. FDA Advisory Panel recommends approval of RADIESSE for two facial aesthetic applications

Business Update - U.S. FDA approves wavefront-guided excimer laser system to correct eye conditions

Business Update - U.S. FDA conditionally approves modification of IDE endpoint for U.S. migraine implant study

Cancer Therapy - Proteasome inhibition is new therapy for non-Hodgkin lymphoma

Chronic Fatigue Syndrome - Cognitive dysfunction is linked to mental fatigue in chronic fatigue syndrome patients

Chronic Lymphocytic Leukemia - Genta briefing documents posted for U.S. FDA panel review of Genasense application

Clinical Trials - Starpharma initiates U.S. NIH-funded trial of microbicide for sexually transmitted diseases

Depression - Antidepressant-drug interactions are rarely clinically significant

Dermatology - Connetics reports positive results from second Phase III clinical trial of Extina Foam, 2%

Drug Abuse - Deaths from fentanyl-laced heroin overdoses highlight need for opioid addiction treatment

Drug Abuse - U.S. FDA grants clearance for OTC home use drug tests for marijuana, cocaine, others

Drug Development - OrthoLogic announces results of preliminary analysis of Phase IIb trial of Chrysalin

Drug Development - Photocleavage of o-nitrobenzyl ether derivatives allows rapid biomedical release

Drug Development - Reversed amide derivatives of arachidonoyl ethanolamide have been synthesized

Drug Development - U.S. FDA proposes new rule to automate drug registration and listing

Drug Resistance - Calcium channel blockers are substrates of multidrug resistance-linked ABC drug transporter

Encephalomyelitis -  Streptococcus pneumoniae infection aggravates autoimmune encephalomyelitis

Environmental Health - Bottled water is safe under U.S. FDA's comprehensive regulatory system

Epilepsy - Anti-epileptic drug rufinamide improves cognitive function

Epilepsy - Sleep disturbances exacerbate partial-onset epilepsy

Finance - Nastech receives small business grant to develop RNAi therapeutics for influenza

Food Safety - Survival of Listeria monocytogenes in uncooked Italian salami was investigated

Foot-and-Mouth Disease - Method to detect antibodies to proteins of foot-and-mouth disease virus has been developed

Generic Drugs - Mylan receives tentative approval for generic Fluoxetine capsules for premenstrual disorder

HIV/AIDS Research - U.S FDA grants SPA for second phase 3 trial of HIV-associated lipodystrophy drug

HIV/AIDS Therapy - People with HIV/AIDS may migrate to obtain support and medical care

HIV/AIDS Transmission - Some HIV-1 genotypes increase risk of HIV transmission by breast-feeding

Headache & Migraine - Sick leave is related to migraine and non-migrainous headache frequency

Health Insurance - Individuals enrolled in HMOs have more doctor and emergency department visits per year

Healthcare Access - Case-mix payment increases access to care for higher acuity Medicaid residents

Imaging - Quest International announces clearance for ME551i2 5MP monochrome digital mammography display

Imaging - Risk of contrast-induced nephropathy is highest for iohexol

Immunology - T cell response to pulmonary Cryptococcus neoformans infection is diverse

Influenza Vaccine - Protein Sciences licenses FluBlOk to UMN Pharma for Japan market

Legal Issues - U.S. marshals seize defective Alaris infusion pumps made by Cardinal Health Care 303, Inc.

Malaria - Financial and clinical implications of malaria diagnosis using microscopy in Kenya were examined

Malaria - Malaria treatment error predictors for children in Malawi are determined

Malaria - Mitochondrial peroxiredoxin from Plasmodium has been characterized

Malignant Mesothelioma - Alfacell updates progress on development of Onconase in cancer

Market Analysis - All eyes are on Plan B's over-the-counter switch

Measles Vaccine - Time to intervene with vaccination campaign may be longer than thought during measles epidemic

Medical Devices - Advisories on defibrillators and accessories occur frequently

Medical Devices - Stryker receives U.S. FDA clearance for anatomic femoral heads with X3 polyethylene liners

Mental Health - Intervention efforts among serial bullies can eliminate origin of a school's forms of violence

Mental Health - Obsessive-compulsive disorder adversely impacts quality of life