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SARS Vaccine

Long-lived memory T cell responses to SARS antigen in recovered SARS patients are described

Published in Medical Letter on the CDC and FDA, October 8th, 2006

A recent report describes long-lived effector/central memory T-cell responses to severe acute respiratory syndrome coronavirus (SARS-CoV) S antigen in recovered SARS patients.

According to that report from researchers in China and the United States, "The role of cell-mediated immunity in human SARS-CoV infection is still not well understood. In this study, we found that memory T-cell responses against the spike (S) protein were persistent for more than one year after SARS-CoV infection by detecting the production of IFN-gamma using ELISA and ELISpot assays."

Flow cytometric analysis showed that both CD4+ and CD8+ T cells were involved in cellular...

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