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HIV/AIDS Epidemiology

HIV-1 inter-subtype recombinants can be transmitted vertically to infants

Published in Medical Letter on the CDC and FDA, October 22nd, 2006

Researchers report results of an analysis of HIV-1 sequences vertically transmitted to infants in Kisumu, Kenya.

According to a report from Australia, "HIV-1 prevalence in Kenya among women aged between 15-19 years is approximately 23%. These women are prospective mothers and therefore can play an important role in mother-to-child transmission of HIV. The risk of a seropositive mother transmitting the virus to her infant is 25-35% in developing countries, such as Kenya, where antiretroviral drugs are not readily available."

"This study was undertaken to evaluate the molecular nature of HIV-1 strains, assess recombination, and its relevance in...

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