Drug Development

Sequential genome-wide association test for analyzing adverse drug events is developed

Published in Medical Letter on the CDC and FDA, November 19th, 2006

Scientists have developed a sequential genome-wide association test for analyzing adverse drug events as they arise.

According to a study from England, "Pharmacovigilance, the monitoring of adverse events (AEs), is an integral part in the clinical evaluation of a new drug. Until recently, attempts to relate the incidence of AEs to putative causes have been restricted to the evaluation of simple demographic and environmental factors. The advent of large-scale genotyping, however, provides an opportunity to look for associations between AEs and genetic markers, such as single nucleotides polymorphisms (SNPs)."

"It is envisaged that a very large number...

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Source: Medical Letter on the CDC and FDA (2006-11-19)

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