Clinical Trials
Eculizumab shows significant improvement in open-label Phase III SHEPHERD study in PNH patients
Published in Medical Letter on the CDC and FDA, January 14th, 2007
Eculizumab, a novel monoclonal antibody investigational drug developed by Alexion Pharmaceuticals, Inc. (ALXN), appeared to be safe and well tolerated and provided clinically and statistically significant improvements in intravascular hemolysis, anemia, fatigue and quality of life in patients with paroxysmal nocturnal hemoglobinuria (PNH) during the 52 weeks of treatment in the Phase III SHEPHERD open-label clinical trial.
These results were presented at the 48th Annual Proceedings of the American Society of Hematology in Orlando, Florida.
PNH, a rare and life-threatening form of hemolytic anemia, is an acquired genetic blood disorder characterized...
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