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Anemia

Phase II data show promise of Aranesp treatment for anemia of cancer

Published in Medical Letter on the CDC and FDA, January 14th, 2007

Amgen (AMGN) announced final results of a 17-week randomized, double-blind, placebo-controlled, Phase II study evaluating Aranesp (darbepoetin alfa) administered every four weeks for the treatment of anemia in cancer patients not undergoing chemotherapy and/or myelosuppressive radiotherapy, a condition known as anemia of cancer.

Patients receiving Aranesp were nearly three times more likely to achieve a hematopoietic response than patients receiving a placebo.

Researchers reported results for 218 patients treated with Aranesp (n=162) or placebo (n=56) for up to 17 weeks. The study's primary endpoint was the percentage of patients with a hematopoietic...

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