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Anthrax Vaccines

Scientists at University of Virginia, Health Science Center publish research in anthrax vaccines

Published in Medical Letter on the CDC and FDA, January 14th, 2007

A report, "Low doses of antigen coupled to anti-CR2 mAbs induce rapid and enduring IgG immune responses in mice and in cynomolgus monkeys," is newly published data in Molecular Immunology. "The complement system and B cell complement receptor 2 (CR2), specific for C component C3dg, play important roles in both the innate and adaptive immune response. We used hapten and protein conjugates of anti-CR2 mAbs as models for C3dg-opsonized antigens and immune complexes to examine the handling of and immune response to these reagents in mice and in non-human primates (NHP)," scientists in the United States report.

"Mice immunized and boosted i.v. with only 100 ng of Alexa 488...

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